Regulation of water flow in the ocular lens: new roles for aquaporins
PJ Donaldson, RS Petrova, N Nair… - The Journal of …, 2024 - Wiley Online Library
The ocular lens is an important determinant of overall vision quality whose refractive and
transparent properties change throughout life. The lens operates an internal microcirculation …
transparent properties change throughout life. The lens operates an internal microcirculation …
[HTML][HTML] Alterations in lens free water distribution are associated with shape deformation in accommodation
Objective To investigate whether a redistribution of water within the crystalline lens is
associated with the shape deformation that occurs during accommodation. Design …
associated with the shape deformation that occurs during accommodation. Design …
Optical development in the murine eye lens of accelerated senescence-prone SAMP8 and senescence-resistant SAMR1 strains
The eye lens is responsible for focusing objects at various distances onto the retina and its
refractive power is determined by its surface curvature as well as its internal gradient …
refractive power is determined by its surface curvature as well as its internal gradient …
[HTML][HTML] Connexin 50 Influences the Physiological Optics of the In Vivo Mouse Lens
Purpose: The purpose of this study was to utilize multi-parametric magnetic resonance
imaging (MRI) to investigate in vivo age-related changes in the physiology and optics of …
imaging (MRI) to investigate in vivo age-related changes in the physiology and optics of …
A First-Passage Model of Intravitreal Drug Delivery and Residence Time—Influence of Ocular Geometry, Individual Variability, and Injection Location
P Lamirande, EA Gaffney, M Gertz… - … & Visual Science, 2024 - iovs.arvojournals.org
Purpose: Standard of care for various retinal diseases involves recurrent intravitreal
injections. This motivates mathematical modeling efforts to identify influential factors for …
injections. This motivates mathematical modeling efforts to identify influential factors for …
A first passage model of intravitreal drug delivery and residence time, in relation to ocular geometry, individual variability, and injection location
P Lamirande, EA Gaffney, M Gertz, PK Maini… - arXiv preprint arXiv …, 2024 - arxiv.org
Purpose: Standard of care for various retinal diseases involves recurrent intravitreal
injections. This motivates mathematical modelling efforts to identify influential factors for drug …
injections. This motivates mathematical modelling efforts to identify influential factors for drug …
Deafness, Skin Disease & Cataract
TW White - sites.google.com
Our research focuses on the intercellular communication provided by gap junction channels,
how it is regulated by intracellular signaling cascades, and the human diseases that result …
how it is regulated by intracellular signaling cascades, and the human diseases that result …