The role of microenvironment in tumor angiogenesis

X Jiang, J Wang, X Deng, F Xiong, S Zhang… - Journal of Experimental …, 2020 - Springer
Tumor angiogenesis is necessary for the continued survival and development of tumor cells,
and plays an important role in their growth, invasion, and metastasis. The tumor …

IL-1 family cytokine regulation of vascular permeability and angiogenesis

E Fahey, SL Doyle - Frontiers in Immunology, 2019 - frontiersin.org
The IL-1 family of cytokines are well-known for their primary role in initiating inflammatory
responses both in response to and acting as danger signals. It has long been established …

Role of cytokines and chemokines in angiogenesis in a tumor context

M Geindreau, M Bruchard, F Vegran - Cancers, 2022 - mdpi.com
Simple Summary Tumor growth in solid cancers requires adequate nutrient and oxygen
supply, provided by blood vessels created by angiogenesis. Numerous studies have …

Neutrophils activated by membrane attack complexes increase the permeability of melanoma blood vessels

X Liu, Y Wang, AT Bauer, M Kirschfink… - Proceedings of the …, 2022 - National Acad Sciences
The microenvironment of malignant melanomas defines the properties of tumor blood
vessels and regulates infiltration and vascular dissemination of immune and cancer cells …

Modulation of HMGB1 translocation and RAGE/NFκB cascade by quercetin treatment mitigates atopic dermatitis in NC/Nga transgenic mice

V Karuppagounder, S Arumugam… - Experimental …, 2015 - Wiley Online Library
Quercetin, glycosylated form of flavonoid compound, has potent antioxidant and anti‐
inflammatory properties. In this study, we have investigated the effects of quercetin on skin …

Melanoma plasticity: promoter of metastasis and resistance to therapy

F Huang, F Santinon, RE Flores González… - Frontiers in …, 2021 - frontiersin.org
Melanoma is the deadliest form of skin cancer. Although targeted therapies and
immunotherapies have revolutionized the treatment of metastatic melanoma, most patients …

Differential macular features on optical coherence tomography angiography in eyes with choroidal nevus and melanoma

A Valverde-Megías, EAT Say, SR Ferenczy, CL Shields - Retina, 2017 - journals.lww.com
Purpose: To evaluate optical coherence tomography angiography (OCTA) characteristics of
macular vascular details in eyes with choroidal nevus and melanoma, compared with …

CCL2 is a vascular permeability factor inducing CCR2-dependent endothelial retraction during lung metastasis

M Roblek, D Protsyuk, PF Becker, C Stefanescu… - Molecular Cancer …, 2019 - AACR
Increased levels of the chemokine CCL2 in cancer patients are associated with poor
prognosis. Experimental evidence suggests that CCL2 correlates with inflammatory …

Interplay Between Extracellular Matrix Remodeling and Angiogenesis in Tumor Ecosystem

R Siddhartha, M Garg - Molecular Cancer Therapeutics, 2023 - AACR
Studying the complex mechanisms of tumorigenesis and examining the interactions of
neoplastic cells within tumor ecosystem are critical to explore the possibility of effective …

New interfaces of thyroid hormone actions with blood coagulation and thrombosis

PJ Davis, SA Mousa… - Clinical and Applied …, 2018 - journals.sagepub.com
Substantial clinical evidence indicates hyperthyroidism enhances coagulation and
increases the risk of thrombosis. In vitro and clinical evidence implicate multiple …