Chronic exposure to alcohol produces changes in the prefrontal cortex that are thought to
contribute to the development and maintenance of alcoholism. A large body of literature …

The cortical-striatal brain circuitry is heavily implicated in drug-use. As such, the present
study investigated the functional role of cortical-striatal circuitry in modulating alcohol self …

Background Alcohol affects multiple circuits in the brain, mainly disrupting the delicate
balance between inhibitory γ‐aminobutyric acid (GABA) transmission and excitatory …

Developing efficacious treatments for alcohol use disorder (AUD) has proven difficult. The
insidious nature of the disease necessitates a deep understanding of its underlying biology …

Post-traumatic stress disorder (PTSD) is a psychiatric illness that can increase the risk for
developing an alcohol use disorder (AUD). While clinical data has been useful in identifying …

Background: The basolateral amygdala plays a critical role in the etiology of anxiety
disorders and addiction. Pyramidal neurons, the primary output cells of this region, display …

Rationale Varenicline, a smoking-cessation agent, may be useful in treating alcohol use
disorders. An important consideration when studying factors that influence drinking/relapse …

The Shenmen point (acupuncture point heart 7: HT7), located in the heart meridian, is
frequently used to treat mental disorders, including drug addiction, anxiety, and depression …

Rationale Hypothalamic-pituitary-adrenal (HPA) axis hormones have neuroactive
metabolites with receptor activity similar to ethanol. Objectives The present study related …

Gabapentin, a drug used in the treatment of epileptic seizures and neuropathic pain, has
shown efficacy in the treatment of alcohol dependence. Moreover, given that gabapentin is …