Like the obesity epidemic, our understanding of adipocytes and adipose tissue is
expanding. Just in the past decade, substantial advances have led to new insights into the …

Adipose tissue is now recognized as an important endocrine organ, capable of secreting a
large number of endocrine factors which regulate a wide variety of physiological functions …

Cardiovascular disease (CVD) is the leading cause of death globally. Risk assessment is
crucial for identifying at-risk individuals who require immediate attention as well as to guide …

Diabetes is associated with an increased risk of heart failure (HF). This is commonly termed
diabetic cardiomyopathy and is often characterised by increased cardiac fibrosis …

The myocardium consists of different cell types, of which endothelial cells, cardiomyocytes,
and fibroblasts are the most abundant. Communication between these different cell types …

Aims Fibroblast growth factor 21 (FGF21) is a hepatic metabolic regulator with pleotropic
actions. Its plasma concentrations are increased in obesity and diabetes; states associated …

Conquering obesity has become a major socioeconomic challenge. Here, we show that
reduced expression of the miR-25-93-106b cluster, or miR-93 alone, increases fat mass …

Metabolic cardiovascular diseases have become a global health concern, and some of their
risk factors are linked to several metabolic disorders. They are the leading causes of death …

Background Adiponectin (AD) cardioprotective activities are mediated by AMPK, a fuel-
sensing molecule sharing common targets and cellular activities with SIRT-1. Whether AD …

Adiponectin is an adipocyte-derived hormone that plays a critical role in energy
homeostasis, mainly attributed to its insulin-sensitizing properties. Accumulating studies …