SOX10 belongs to a family of 20 SRY (sex-determining region Y)-related high mobility group
box-containing (SOX) proteins, most of which contribute to cell type specification and …

Abstract Sox8, Sox9 and Sox10 represent the three vertebrate members of the SoxE
subclass of high-mobility-group domain containing Sox transcription factors. They play …

Neural crest cells (NCCs) are a dynamic, multipotent, vertebrate-specific population of
embryonic stem cells. These ectodermally-derived cells contribute to diverse tissue types in …

The craniofacial skeletal structures that comprise the human head develop from multiple
tissues that converge to form the bones and cartilage of the face. Because of their complex …

Purpose To investigate the correlation between chemoresistance of colorectal cancer to 5-
fluorouracil and BNIP3 and the underlying mechanism. Methods BNIP3 protein in …

Intratumoral heterogeneity is caused by genomic instability and phenotypic plasticity, but
how these features co-evolve remains unclear. SOX10 is a neural crest stem cell (NCSC) …

Neural crest (NC) cells are a stem‐like multipotent population of progenitor cells that are
present in vertebrate embryos, traveling to various regions in the developing organism …

Digits shape is sculpted by interdigital programmed cell death during limb development.
Here, we show that DNA breakage in the periphery of 5-methylcytosine nuclei foci of …

The neural tube is the primordium of the central nervous system (CNS) in which its
development is not entirely clear. Understanding the cellular and molecular basis of neural …

Folate deficiency has been known to contribute to neural tube and neural crest defects, but
why these tissues are particularly affected, and which are the molecular mechanisms …