[HTML][HTML] Developing fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity
X Meng, Y Fang, M Ding, Y Zhang, K Jia, Z Li… - Biotechnology …, 2022 - Elsevier
Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …
notably for therapeutic agent development. Genome sequencing revealed that the number …
Efficient de novo assembly and modification of large DNA fragments
S Jiang, Y Tang, L Xiang, X Zhu, Z Cai, L Li… - Science China Life …, 2022 - Springer
Synthetic genomics has provided new bottom-up platforms for the functional study of viral
and microbial genomes. The construction of the large, gigabase (Gb)-sized genomes of …
and microbial genomes. The construction of the large, gigabase (Gb)-sized genomes of …
[PDF][PDF] 后基因组时代害虫生防真菌次级代谢产物的研究进展
亓兰达， 魏鹏霖， 张晗星， 陈国参， 张英涛… - 中国科学: 生命 …, 2020 - researchgate.net
摘要真菌次级代谢产物在害虫生物防治方面起着重要作用, 而其中起杀虫作用的主要活性物质越
来越受到人们关注. 近几年随着测序技术的发展, 利用基因组和生物信息技术挖掘真菌次级代谢 …
来越受到人们关注. 近几年随着测序技术的发展, 利用基因组和生物信息技术挖掘真菌次级代谢 …
膨大弯颈霉中与Bmt 生物合成相关的PKS 基因功能研究.
杨秀青， 李丝竹， 徐康， 刘美洁， 郭立忠… - Mycosystema, 2023 - search.ebscohost.com
环孢霉素A 是一种主要由膨大弯颈霉Tolypocladium inflatum 产生的环肽类次级代谢产物,
临床上被广泛用作免疫抑制剂, 其合成需要特殊底物(4R)-4-[(E)-2-butenyl]-4-methyl-L …
临床上被广泛用作免疫抑制剂, 其合成需要特殊底物(4R)-4-[(E)-2-butenyl]-4-methyl-L …
Recent technology advancements in large‐scale DNA assembly.
The article discusses recent advancements in large-scale DNA assembly, focusing on the
synthesis of genomes from kilobase-sized viruses to megabase-sized bacteria and yeast …
synthesis of genomes from kilobase-sized viruses to megabase-sized bacteria and yeast …
[PDF][PDF] Genetic mining of the “dark matter” in fungal natural products
W Li, WB Yin - Sci. China Life Sci, 2019 - researchgate.net
Filamentous fungi are one of the major sources of natural products (NPs; which are also
termed as secondary metabolites (SMs)) with diverse biological activities, which have been …
termed as secondary metabolites (SMs)) with diverse biological activities, which have been …
Engineering Aspergillus oryzae for the production of biosynthetic proteins
Y Sun - 2024 - repo.uni-hannover.de
This investigation aims to strategically engineer the biosynthesis of fungal natural products
through heterologous expression. It includes modifications to the heterologous host to boost …
through heterologous expression. It includes modifications to the heterologous host to boost …