The direct α-amination of carbonyl compounds using organocatalysts represents a powerful
and atom-economical tool for asymmetric C–N bond formation. We describe a complete …

Starting from an l-serine-derived multifunctional aminobutenolide as a common chiral
building block, stereoselective synthetic routes to representative examples of di-, tri-, and …

An enantioselective route towards the synthesis of C-1 substituted tetrahydroisoquinoline
natural products is reported. Six different natural products are synthesized from a single …

Enantiomeric 2, 3, 4-tris (hydroxyalkyl)-5-phenylpyrrolidines have been synthesized from the
major cycloadducts obtained by the 1, 3-dipolar cycloaddition of sugar enones with …

Enantioselective syntheses of (R)‐antofine and (R)‐cryptopleurine starting from a 3‐
phenanthrenylpropanal derivative are reported. Asymmetric α‐amination of this aldehyde is …

A new class of nitrogen-containing endoperoxides were synthesised by a photochemical [4+
2]-cycloaddition between a diene and singlet oxygen. The endoperoxides were …

This chapter aims to provide an overview of the key synthetic methods, reactions, and
applications reported in 2015 in the area of seven-membered heterocyclic compounds. Most …

A concise organocatalytic route toward the synthesis of furanose and pyranose substituted
glycine and alanine derivatives is reported. These compounds are core structural units of …

The synthesis of six-, seven-, and eight-membered cis-dihydroxy azacycles has been
accomplished from d-ribose using Vasella reductive amination as a key step and utilization …

The synthetic utility of proline‐catalyzed asymmetric α‐hydroxylation and subsequent
reductive amination of aldehydes to afford chiral β‐amino alcohols is explored for the first …