[HTML][HTML] Targeting abnormal lipid metabolism of T cells for systemic lupus erythematosus treatment

JQ Hu, YH Yan, H Xie, XB Feng, WH Ge, H Zhou… - Biomedicine & …, 2023 - Elsevier
Systemic lupus erythematosus (SLE) is an autoimmune disease in which the immune
system attacks its own tissues and organs. However, the causes of SLE remain unknown …

[HTML][HTML] Targeting immunometabolism by active ingredients derived from traditional Chinese medicines for treatment of rheumatoid arthritis

Y He, C Mai, H Pan, L Liu, H Zhou, Y Xie - Chinese Herbal Medicines, 2021 - Elsevier
Rheumatoid arthritis (RA), the most common inflammatory arthropathy word wild, is a
systemic autoimmune disease that mainly affects the synovium of joints with a high disability …

Prediction of the endocrine-disrupting ability of 49 per-and polyfluoroalkyl substances: In silico and epidemiological evidence

S Yu, J Ren, Z Lv, R Li, Y Zhong, W Yao, J Yuan - Chemosphere, 2022 - Elsevier
The toxic effects of per-and polyfluoroalkyl substances (PFASs) on humans are mediated by
nuclear hormone receptors (NHRs). However, data on the interaction of PFASs and NHRs is …

[HTML][HTML] Integrated metabolomics and network analysis reveal changes in lipid metabolisms of tripterygium glycosides tablets in rats with collagen-induced arthritis

Y Gao, Q Qian, G Xun, J Zhang, S Sun, X Liu… - Computational and …, 2023 - Elsevier
Tripterygium glycosides tablets (TGT) are the commonly used preparation for rheumatoid
arthritis (RA). However, the changes in TGT on RA are still unclear at the metabolic level …

Endocytosis of LXRs: Signaling in liver and disease

M Brahma, S Ghosal, M Maruthi, SK Kalangi - Progress in Molecular …, 2023 - Elsevier
Nuclear receptors are among one of the major transcriptional factors that induces gene
regulation in the nucleus. Liver X receptor (LXR) is a transcription factor which regulates …

[PDF][PDF] Effect of Methotrexate on Liver in Patient with Rheumatoid Arthritis

H Ahmad, M Fatima, A Ali, A Awan… - Saudi J Pathol …, 2022 - academia.edu
Background: Methotrexate helps your immune system from assaulting your body's cells by
calming it down. This helps to lessen the inflammation that causes rheumatoid arthritis's …