Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: a review

C Proença, D Ribeiro, M Freitas… - Critical Reviews in Food …, 2022 - Taylor & Francis
Abstract Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide
and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α …

Flavonoids as dual-target inhibitors against α-glucosidase and α-amylase: a systematic review of in vitro studies

TP Lam, NVN Tran, LHD Pham, NVT Lai… - Natural Products and …, 2024 - Springer
Diabetes mellitus remains a major global health issue, and great attention is directed at
natural therapeutics. This systematic review aimed to assess the potential of flavonoids as …

Effects of hydroxylation at C3′ on the B ring and diglycosylation at C3 on the C ring on flavonols inhibition of α-glucosidase activity

Y Qin, X Chen, F Xu, C Gu, K Zhu, Y Zhang, G Wu… - Food Chemistry, 2023 - Elsevier
The structure–activity relationship and inhibitory mechanism of flavonols on α-glucosidase
were studied by inhibition kinetics, multispectral study, and molecular docking. The flavonols …

Hesperetin's health potential: Moving from preclinical to clinical evidence and bioavailability issues, to upcoming strategies to overcome current limitations

B Salehi, N Cruz-Martins, M Butnariu… - Critical Reviews in …, 2022 - Taylor & Francis
Flavonoids are common in the plant kingdom and many of them have shown a wide
spectrum of bioactive properties. Hesperetin (Hst), the aglycone form of hesperidin, is a …

Control of eriocitrin release from pH-sensitive gelatin-based microgels to inhibit α-glucosidase: an experimental and computational study

M Sadeghi, M Sheikhi, M Miroliaei - Food & Function, 2022 - pubs.rsc.org
α-Glucosidase is among the intestinal epithelial enzymes that produce absorbable glucose
in the final stage of glycan catabolism. It leads to an increase in blood glucose levels as a …

Exploring the inhibitory properties of biflavonoids on α-glucosidase; computational and experimental approaches

M Sadeghi, M Miroliaei, M Ghanadian… - International Journal of …, 2023 - Elsevier
Biflavonoids (BFs) are a group of polyphenols that have a unique biochemical structure. One
of the key biomedical mechanisms that BFs can have high potential in managing Diabetes …

Determination of bioactive components in mandarin fruits: A review

MS Bureš, L Maslov Bandić… - Critical reviews in …, 2023 - Taylor & Francis
During the last decade, there has been a continuous rise in the consumption of fresh easy-to-
peel mandarins. However, the majority of the knowledge comes from other citrus fruit, like …

Ameliorative Effect of Ocimum forskolei Benth on Diabetic, Apoptotic, and Adipogenic Biomarkers of Diabetic Rats and 3T3-L1 Fibroblasts Assisted by In Silico …

HE Khalil, MF Abdelwahab, PM Emeka… - Molecules, 2022 - mdpi.com
Diabetes mellitus (DM) is a complicated condition that is accompanied by a plethora of
metabolic symptoms, including disturbed serum glucose and lipid profiles. Several herbs are …

Medicinal importance, pharmacological activities and analytical aspects of a flavonoid glycoside 'Nicotiflorin'in the medicine

DK Patel - Drug Metabolism and Bioanalysis Letters Formerly …, 2022 - benthamdirect.com
Background: Herbal products are derived from different natural sources, mainly used as a
source of food material and medicine in the health sectors since ancient times. Herbal …

[HTML][HTML] Flowers: precious food and medicine resources

X Liu, S Wang, L Cui, H Zhou, Y Liu, L Meng… - Food Science and …, 2023 - Elsevier
Flower plants are popular all over the world and important sources of ornamental plants,
bioactive molecules and nutrients. Flowers have a wide range of biological activities and …