The past decade has witnessed a consolidation and refinement of the extraordinary
progress made in taste research. This Review describes recent advances in our …

Sweetness is the preferred taste of humans and many animals, likely because sugars are a
primary source of energy. In many mammals, sweet compounds are sensed in the tongue by …

In humans little is known as to whether taste solutions applied to the tongue elicit cephalic
phase insulin release (CPIR). The aim of this study was to re-examine if any effect of …

Previous work from our lab has demonstrated that experience with high-intensity sweeteners
in rats leads to increased food intake, body weight gain and adiposity, along with diminished …

Recent results from both human epidemiological and experimental studies with animals
suggest that intake of noncaloric sweeteners may promote, rather than protect against …

The global prevalence of type 2 diabetes mellitus and impaired glucose metabolism
continues to rise in conjunction with the pandemic of obesity. The metabolic Roux‐en‐Y …

Food anticipatory hormonal responses (cephalic responses) are proactive physiological
processes, that allow animals to prepare for food ingestion by modulating their hormonal …

The act of eating and drinking brings food-related chemicals into contact with taste cells.
Activation of these taste cells, in turn, engages neural circuits in the central nervous system …

The cephalic phase insulin response (CPIR) is classically defined as a head receptor-
induced early release of insulin during eating that precedes a postabsorptive rise in blood …

Sensory stimulation from foods elicits cephalic phase responses, which facilitate digestion
and nutrient assimilation. One such response, cephalic-phase insulin release (CPIR) …