Cereal polyphenols inhibition mechanisms on advanced glycation end products and regulation on type 2 diabetes

L Dong, Y Li, Q Chen, Y Liu, Z Wu, D Pan… - Critical Reviews in …, 2024 - Taylor & Francis
Advanced glycation end products (AGEs), the products of non-enzymatic browning reactions
between the active carbonyl groups of reducing sugars and the free amines of amino acids …

Updates on the chemistry, processing characteristics, and utilization of tea flavonoids in last two decades (2001-2021)

J Shi, G Yang, Q You, S Sun, R Chen, Z Lin… - Critical Reviews in …, 2023 - Taylor & Francis
Tea flavonoids are widely recognized as critical flavor contributors and crucial health-
promoting bioactive compounds, and have long been the focus of research worldwide in …

Polyphenols: bioavailability, microbiome interactions and cellular effects on health in humans and animals

MB Scott, AK Styring, JSO McCullagh - Pathogens, 2022 - mdpi.com
Polyphenolic compounds have a variety of functions in plants including protecting them from
a range of abiotic and biotic stresses such as pathogenic infections, ionising radiation and …

[HTML][HTML] Sample preparation strategies for mass spectrometry analysis in human exposome research: current status and future perspectives

Y Gu, JT Peach, B Warth - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The exposome is the measure of total environmental exposures and has a significant impact
on human health outcomes. Exposomics research typically examines complex biological …

[HTML][HTML] Mycotoxin-mixture assessment in mother-infant pairs in Nigeria: From mothers' meal to infants' urine

D Braun, WA Abia, B Šarkanj, M Sulyok, T Waldhoer… - Chemosphere, 2022 - Elsevier
Exposure to food and environmental contaminants is a global environmental health issue. In
this study, innovative LC-MS/MS approaches were applied to investigate mycotoxin co …

Immobilized enzymes on magnetic beads for separate mass spectrometric investigation of human phase II metabolite classes

I Tsiara, A Riemer, MSP Correia… - Analytical …, 2023 - ACS Publications
The human body has evolved to remove xenobiotics through a multistep clearance process.
Non-endogenous metabolites are converted through a series of phase I and different phase …

Exposomic biomonitoring of polyphenols by non-targeted analysis and suspect screening

I Oesterle, M Pristner, S Berger, M Wang… - Analytical …, 2023 - ACS Publications
Polyphenols, prevalent in plants and fungi, are investigated intensively in nutritional and
clinical settings because of their beneficial bioactive properties. Due to their complexity …

A complexed crystal structure of a single-stranded DNA-binding protein with quercetin and the structural basis of flavonol inhibition specificity

ES Lin, RH Luo, CY Huang - International Journal of Molecular Sciences, 2022 - mdpi.com
Single-stranded DNA (ssDNA)-binding protein (SSB) plays a crucial role in DNA replication,
repair, and recombination as well as replication fork restarts. SSB is essential for cell …

[HTML][HTML] Quantifying up to 90 polyphenols simultaneously in human bio-fluids by LC-MS/MS

I Oesterle, D Braun, A Rompel, B Warth - Analytica chimica acta, 2022 - Elsevier
Establishing a method for human biomonitoring (HBM) of polyphenols enables the
assessment of internal concentrations of these food bio-actives and the correlation with …

[HTML][HTML] Elucidation of xenoestrogen metabolism by non-targeted, stable isotope-assisted mass spectrometry in breast cancer cells

M Flasch, C Bueschl, G Del Favero, G Adam… - Environment …, 2022 - Elsevier
Environmental exposure to xenoestrogens, ie, chemicals that imitate the hormone 17β-
estradiol, has the potential to influence hormone homeostasis and action. Detailed …