Transcribing RNA Polymerase II interacts with multiple factors that orchestrate maturation
and stabilisation of messenger RNA. For the majority of noncoding RNAs, the polymerase …

E-cadherin and P-cadherin are major contributors to cell–cell adhesion in epithelial tissues,
playing pivotal roles in important morphogenetic and differentiation processes during …

Although microRNAs (miRNAs), other non-coding RNAs (ncRNAs)(eg lncRNAs,
pseudogenes and circRNAs) and competing endogenous RNAs (ceRNAs) have been …

Abstract Ensembl (http://www. ensembl. org) is a genomic interpretation system providing
the most up-to-date annotations, querying tools and access methods for chordates and key …

An essential prerequisite for any systems-level understanding of cellular functions is to
correctly uncover and annotate all functional interactions among proteins in the cell. Toward …

Abstract Changes in gene expression are thought to underlie many of the phenotypic
differences between species. However, large-scale analyses of gene expression evolution …

Genomic experiments produce multiple views of biological systems, among them are DNA
sequence and copy number variation, and mRNA and protein abundance. Understanding …

While the number and identity of proteins expressed in a single human cell type is currently
unknown, this fundamental question can be addressed by advanced mass spectrometry …

Abstract The International Cancer Genome Consortium (ICGC) was launched to coordinate
large-scale cancer genome studies in tumors from 50 different cancer types and/or subtypes …

We describe the draft genome of the microcrustacean Daphnia pulex, which is only 200
megabases and contains at least 30,907 genes. The high gene count is a consequence of …