The blood–brain barrier: structure, regulation, and drug delivery

D Wu, Q Chen, X Chen, F Han, Z Chen… - Signal transduction and …, 2023 - nature.com
Blood–brain barrier (BBB) is a natural protective membrane that prevents central nervous
system (CNS) from toxins and pathogens in blood. However, the presence of BBB …

Electroactive biomaterials and systems for cell fate determination and tissue regeneration: design and applications

Z Liu, X Wan, ZL Wang, L Li - Advanced Materials, 2021 - Wiley Online Library
During natural tissue regeneration, tissue microenvironment and stem cell niche including
cell–cell interaction, soluble factors, and extracellular matrix (ECM) provide a train of …

Stimuli-responsive polymeric nanocarriers for drug delivery, imaging, and theragnosis

SS Das, P Bharadwaj, M Bilal, M Barani, A Rahdar… - Polymers, 2020 - mdpi.com
In the past few decades, polymeric nanocarriers have been recognized as promising tools
and have gained attention from researchers for their potential to efficiently deliver bioactive …

Ultrasound‐activated sensitizers and applications

X Lin, J Song, X Chen, H Yang - … Chemie International Edition, 2020 - Wiley Online Library
Modalities for photo‐triggered anticancer therapy are usually limited by their low penetrative
depth. Sonotheranostics especially sonodynamic therapy (SDT), which is different from …

Smart micro/nanoparticles in stimulus-responsive drug/gene delivery systems

M Karimi, A Ghasemi, PS Zangabad… - Chemical Society …, 2016 - pubs.rsc.org
New achievements in the realm of nanoscience and innovative techniques of nanomedicine
have moved micro/nanoparticles (MNPs) to the point of becoming actually useful for …

[HTML][HTML] The smart drug delivery system and its clinical potential

D Liu, F Yang, F Xiong, N Gu - Theranostics, 2016 - ncbi.nlm.nih.gov
With the unprecedented progresses of biomedical nanotechnology during the past few
decades, conventional drug delivery systems (DDSs) have been involved into smart DDSs …

[HTML][HTML] Peptide and protein nanoparticle conjugates: versatile platforms for biomedical applications

CD Spicer, C Jumeaux, B Gupta… - Chemical Society …, 2018 - pubs.rsc.org
Peptide–and protein–nanoparticle conjugates have emerged as powerful tools for
biomedical applications, enabling the treatment, diagnosis, and prevention of disease. In …

Thermoset shape‐memory polyurethane with intrinsic plasticity enabled by transcarbamoylation

N Zheng, Z Fang, W Zou, Q Zhao, T Xie - Angewandte Chemie, 2016 - Wiley Online Library
Thermoset polymers are known for their superior thermomechanical properties, but the
chemical crosslinking typically leads to intractability. This is reflected in the great differences …

Electroactive biomaterials for facilitating bone defect repair under pathological conditions

BC Heng, Y Bai, X Li, LW Lim, W Li, Z Ge… - Advanced …, 2023 - Wiley Online Library
Bone degeneration associated with various diseases is increasing due to rapid aging,
sedentary lifestyles, and unhealthy diets. Living bone tissue has bioelectric properties critical …

Blood–brain barrier shuttle peptides: an emerging paradigm for brain delivery

B Oller-Salvia, M Sánchez-Navarro, E Giralt… - Chemical Society …, 2016 - pubs.rsc.org
Brain delivery is one of the major challenges in drug development because of the high
number of patients suffering from neural diseases and the low efficiency of the treatments …