Therapeutic potential of the purinergic system in major depressive disorder associated with COVID-19

JLB Simões, ACL Galvan, ELM da Silva… - Cellular and Molecular …, 2023 - Springer
Neuroinflammation is closely related to the development of depression, since the latter is
caused, among other factors, by inflammatory processes, mainly related to the activation of …

Unravelling the complexities of depression with medical intelligence: exploring the interplay of genetics, hormones, and brain function

MBB Heyat, F Akhtar, F Munir, A Sultana… - Complex & Intelligent …, 2024 - Springer
Depression is a multifactorial disease with unknown etiology affecting globally. It's the
second most significant reason for infirmity in 2020, affecting about 50 million people …

[HTML][HTML] Reorganization of brain networks as a substrate of resilience: an analysis of cytochrome c oxidase activity in rats

A Begega, IC Lopez, MC Izquierdo, CI Jove… - Neuroscience, 2023 - Elsevier
The unpredictable chronic mild stress (UCMS) model has been used to induce depressive-
like symptoms in animal models, showing adequate predictive validity. Our work aims to …

Physical activity as a promoter of stress resilience: An analysis of behavioral effects and brain connectivity with cytochrome c-oxidase activity in adult male Wistar rats

A Begega, M López, I Cuesta-López, CI Jove… - Pharmacology …, 2024 - Elsevier
Physical activity (PA) is very beneficial for physical and mental health. This study aims to
examine the resilience-inducting effect of PA in adult male Wistar rats exposed to …

TRPA1 participation in behavioral impairment induced by chronic corticosterone administration

GC Pereira, E Piton, J Bornholdt, BM Dos Santos… - …, 2023 - Springer
Rationale Major depressive disorder (MDD) is one of the most diagnosed mental disorders.
Despite this, its pathophysiology remains poorly understood. In this context, basic research …

[PDF][PDF] Reorganization of Brain Networks as a Substrate of Resilience: An Analysis of Cytochrome c Oxidase Activity in Rats

MA Begega Losa, I Cuesta López… - Neuroscience …, 2023 - digibuo.uniovi.es
The unpredictable chronic mild stress (UCMS) model has been used to induce depressive-
like symptoms in animal models, showing adequate predictive validity. Our work aims to …