Spatially distinguished, multiplex nucleic acid analysis of biological specimens
J Frisen, P Stahl, J Lundeberg, GM Cann… - US Patent …, 2022 - Google Patents
A method for spatially tagging nucleic acids of a biological specimen, including steps of (a)
providing a solid support comprising different nucleic acid probes that are randomly located …
providing a solid support comprising different nucleic acid probes that are randomly located …
Spatially encoded biological assays
MS Chee - US Patent 10,982,268, 2021 - Google Patents
Jun. 11, 2019, now Pat. No. 10,494,667, which is a continuation of application No.
16/430,015, filed on Jun. 3, 2019, which is a continuation of application No. 16/414,213, filed …
16/430,015, filed on Jun. 3, 2019, which is a continuation of application No. 16/414,213, filed …
Spatially encoded biological assays
MS Chee - US Patent 10,996,219, 2021 - Google Patents
The present invention provides assays and assay systems for use in spatially encoded
biological assays. The invention provides an assay system comprising an assay capable of …
biological assays. The invention provides an assay system comprising an assay capable of …
Ligation assays in liquid phase
A Stevens, B Seligmann, JM Yeakley… - US Patent …, 2018 - Google Patents
US9856521B2 - Ligation assays in liquid phase - Google Patents US9856521B2 - Ligation
assays in liquid phase - Google Patents Ligation assays in liquid phase Download PDF Info …
assays in liquid phase - Google Patents Ligation assays in liquid phase Download PDF Info …
Methods and systems for determining spatial patterns of biological targets in a sample
MS Chee, DA Routenberg - US Patent 11,046,996, 2021 - Google Patents
The present disclosure provides methods and assay systems for use in spatially encoded
biological assays, including assays to determine a spatial pattern of abundance, expression …
biological assays, including assays to determine a spatial pattern of abundance, expression …
Methods and systems for determining spatial patterns of biological targets in a sample
MS Chee, DA Routenberg - US Patent 10,927,403, 2021 - Google Patents
The present disclosure provides methods and assay systems for use in spatially encoded
biological assays, including assays to determine a spatial pattern of abundance, expres …
biological assays, including assays to determine a spatial pattern of abundance, expres …
Increasing efficiency of spatial analysis in a biological sample
FA Bava - US Patent 11,732,300, 2023 - Google Patents
Disclosed herein are methods of amplifying an analyte in a biological sample using a
bridging oligonucleotide that hybridizes to a captured analyte. The methods disclosed …
bridging oligonucleotide that hybridizes to a captured analyte. The methods disclosed …
Increasing capture efficiency of spatial assays
FA Bava - US Patent 11,898,205, 2024 - Google Patents
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo …
Generating capture probes for spatial analysis
Y Yin, EPR Iyer, Z Bent, S Giacomello… - US Patent …, 2023 - Google Patents
2021-06-10 Assigned to 10X GENOMICS, INC. reassignment 10X GENOMICS, INC.
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors …
Methods for printing cells and generating arrays of barcoded cells
R Bharadwaj - US Patent 11,702,693, 2023 - Google Patents
US11702693B2 - Methods for printing cells and generating arrays of barcoded cells -
Google Patents US11702693B2 - Methods for printing cells and generating arrays of …
Google Patents US11702693B2 - Methods for printing cells and generating arrays of …