Role of oxidative stress in epileptic seizures

EJ Shin, JH Jeong, YH Chung, WK Kim, KH Ko… - Neurochemistry …, 2011 - Elsevier
Oxidative stress resulting from excessive free-radical release is likely implicated in the
initiation and progression of epilepsy. Therefore, antioxidant therapies aimed at reducing …

Oxidative stress-related biomarkers in autism: systematic review and meta-analyses

A Frustaci, M Neri, A Cesario, JB Adams… - Free Radical Biology …, 2012 - Elsevier
Autism spectrum disorders (ASDs) are rarely diagnosed in children younger than 2 years,
because diagnosis is based entirely on behavioral tests. Oxidative damage may play a …

Levetiracetam mechanisms of action: from molecules to systems

IJ Contreras-García, N Cárdenas-Rodríguez… - Pharmaceuticals, 2022 - mdpi.com
Epilepsy is a chronic disease that affects millions of people worldwide. Antiepileptic drugs
(AEDs) are used to control seizures. Even though parts of their mechanisms of action are …

Effect of probiotic supplementation on seizure activity and cognitive performance in PTZ-induced chemical kindling

S Bagheri, A Heydari, A Alinaghipour, M Salami - Epilepsy & Behavior, 2019 - Elsevier
Epilepsy is one of the most common neurological disorders that severely affect life quality of
many people worldwide. Ion transport in the neuronal membrane, inhibitory–excitatory …

Oxidative/nitrosative stress and antidepressants: targets for novel antidepressants

SY Lee, SJ Lee, C Han, AA Patkar, PS Masand… - Progress in Neuro …, 2013 - Elsevier
The brain is an organ predisposed to oxidative/nitrosative stress. This is especially true in
the case of aging as well as several neurodegenerative diseases. Under such …

Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole‐Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway

AM Alvi, LT Al Kury, A Alattar, I Ullah… - Oxidative medicine …, 2021 - Wiley Online Library
Epilepsy is a neurodegenerative brain disorder characterized by recurrent seizure attacks.
Numerous studies have suggested a strong correlation between oxidative stress and …

The role of reactive species in epileptogenesis and influence of antiepileptic drug therapy on oxidative stress

B Martinc, I Grabnar, T Vovk - Current Neuropharmacology, 2012 - ingentaconnect.com
Epilepsy is considered one of the most common neurological disorders. The focus of this
review is the acquired form of epilepsy, with the development process consisting of three …

Antioxidants as a preventive treatment for epileptic process: a review of the current status

B Martinc, I Grabnar, T Vovk - Current neuropharmacology, 2014 - ingentaconnect.com
Epilepsy is known as one of the most frequent neurological diseases, characterized by an
enduring predisposition to generate epileptic seizures. Oxidative stress is believed to …

[HTML][HTML] Effect of lamotrigine, oxcarbazepine and topiramate on cognitive functions and oxidative stress in PTZ-kindled mice

NB Agarwal, NK Agarwal, PK Mediratta, KK Sharma - Seizure, 2011 - Elsevier
Cognitive impairment is frequently observed in epileptic patients. It has been seen that not
only epilepsy but antiepileptic drugs also impair cognitive functions. The present study was …

Antiepileptic drugs: impacts on human serum paraoxonase‐1

Ş Beydemir, Y Demir - Journal of biochemical and molecular …, 2017 - Wiley Online Library
Serum paraoxonase (PON1) is a key enzyme related to high‐density lipoprotein (HDL)‐
cholesterol particle. It can prevent the oxidation of low‐density lipoprotein (LDL) and HDL …