Alzheimer's disease diagnosis from single and multimodal data using machine and deep learning models: Achievements and future directions

A Elazab, C Wang, M Abdelaziz, J Zhang, J Gu… - Expert Systems with …, 2024 - Elsevier
Alzheimer's Disease (AD) is the most prevalent and rapidly progressing neurodegenerative
disorder among the elderly and is a leading cause of dementia. AD results in significant …

Explainable artificial intelligence in Alzheimer's disease classification: A systematic review

V Viswan, N Shaffi, M Mahmud, K Subramanian… - Cognitive …, 2024 - Springer
The unprecedented growth of computational capabilities in recent years has allowed
Artificial Intelligence (AI) models to be developed for medical applications with remarkable …

Artificial intelligence-based diagnosis of Alzheimer's disease with brain MRI images

Z Yao, H Wang, W Yan, Z Wang, W Zhang… - European Journal of …, 2023 - Elsevier
Alzheimer's disease, a primary neurodegenerative condition, predominantly impacts the
elderly and pre-elderly population. This progressive neurological disorder is characterized …

Pipnet3d: Interpretable detection of alzheimer in mri scans

LA De Santi, J Schlötterer, M Scheschenja… - … Conference on Medical …, 2024 - Springer
Abstract Information from neuroimaging examinations is increasingly used to support
diagnoses of dementia, eg, Alzheimer's disease. While current clinical practice is mainly …

Unveiling the decision making process in Alzheimer's disease diagnosis: A case-based counterfactual methodology for explainable deep learning

A Valoor, GR Gangadharan - Journal of Neuroscience Methods, 2025 - Elsevier
Abstract Background The field of Alzheimer's disease (AD) diagnosis is undergoing
significant transformation due to the application of deep learning (DL) models. While DL …

Medical Metaverse, Part 2: Artificial Intelligence Algorithms and Large Language Models in Psychiatry and Clinical Neurosciences

W López-Ojeda, RA Hurley - The Journal of Neuropsychiatry …, 2023 - Am Neuropsych Assoc
FIGURE 2. Progression of electronic large language model (LLM) technology. 1.
Transformer models are probably the basic infrastructure for these technologies (1). 2 …

Applications of interpretable deep learning in neuroimaging: a comprehensive review

L Munroe, M da Silva, F Heidari, I Grigorescu… - Imaging …, 2024 - direct.mit.edu
Clinical adoption of deep learning models has been hindered, in part, because the “black-
box” nature of neural networks leads to concerns regarding their trustworthiness and …

Exploring intricate connectivity patterns for cognitive functioning and neurological disorders: incorporating frequency-domain NC method into fMRI analysis

B Wang… - Cerebral …, 2024 - academic.oup.com
This study extends the application of the frequency-domain new causality method to
functional magnetic resonance imaging analysis. Strong causality, weak causality, balanced …

[HTML][HTML] Disease2Vec: Encoding Alzheimer's progression via disease embedding tree

L Zhang, L Wang, T Liu, D Zhu - Pharmacological Research, 2024 - Elsevier
For decades, a variety of predictive approaches have been proposed and evaluated in terms
of their prediction capability for Alzheimer's Disease (AD) and its precursor–mild cognitive …

Patch-based Intuitive Multimodal Prototypes Network (PIMPNet) for Alzheimer's Disease classification

LA De Santi, J Schlötterer, M Nauta, V Positano… - arXiv preprint arXiv …, 2024 - arxiv.org
Volumetric neuroimaging examinations like structural Magnetic Resonance Imaging (sMRI)
are routinely applied to support the clinical diagnosis of dementia like Alzheimer's Disease …