Abstract Type 2 diabetes (T2DM) is a persistent metabolic disorder rising rapidly worldwide.
It is characterized by pancreatic insulin resistance and β-cell dysfunction. Hyperglycemia …

Adipose tissue, colloquially known as" fat," is an extraordinarily flexible and heterogeneous
organ. While historically viewed as a passive site for energy storage, we now appreciate that …

Initial studies found increased severity of coronavirus disease 2019 (COVID-19), caused by
infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), in patients …

Peroxisome proliferator-activated receptors (PPARs) are fatty acid-activated transcription
factors of nuclear hormone receptor superfamily that regulate energy metabolism. Currently …

Obesity is one of the major health burdens of the 21st century as it contributes to the growing
prevalence of its related comorbidities, including insulin resistance and type 2 diabetes …

The proliferator-activated receptor γ (PPARγ), a member of the nuclear receptor superfamily,
is one of the most extensively studied ligand-inducible transcription factors. Since its …

Abstract Type 2 diabetes (T2D) is a widely prevalent disease with substantial economic and
social impact for which multiple conventional and novel pharmacotherapies are currently …

Adipocyte Regulation of Insulin Sensitivity and the Risk of Type 2 Diabetes | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Abstract The American Diabetes Association and the European Association for the Study of
Diabetes convened a panel to update the prior position statements, published in 2012 and …

Abstract Iron-sulfur (Fe–S) clusters are essential cofactors most commonly known for their
role mediating electron transfer within the mitochondrial respiratory chain. The Fe–S cluster …