Mammalian genomes encode genes for more than 30 phospholipase A2s (PLA2s) or
related enzymes, which are subdivided into several classes including low-molecular-weight …

Among more than 30 members of the phospholipase A 2 (PLA 2) superfamily, secreted PLA
2 (sPLA 2) enzymes represent the largest family, being Ca 2+-dependent low-molecular …

Abstract Phospholipase A2 (PLA2) catalyses the hydrolysis of the sn-2 position of
glycerophospholipids to yield fatty acids and lysophospholipids. So far, more than 30 …

Abstract Phospholipase A 2 (PLA 2) cleave phospholipids preferentially at the sn-2 position,
liberating free fatty acids and lysophospholipids. They are classified into six main groups …

Among the phospholipase A2 (PLA2) superfamily, which typically catalyzes the sn‐2
hydrolysis of phospholipids to yield fatty acids and lysophospholipids, the secreted PLA2 …

Abstract In essence,“phospholipase A 2”(PLA 2) means a group of enzymes that release
fatty acids and lysophospholipids by hydrolyzing the sn-2 position of glycerophospholipids …

Leukotrienes are clearly involved in airway inflammation and certain clinical features of
asthma. Evolving evidence indicates that leukotriene B 4 has an important role in the …

Abstract Phospholipase A2 (PLA2) catalyses the release of arachidonic acid for generation
of lipid mediators of inflammation and is crucial in diverse inflammatory processes. The …

Microenvironment-based alterations in phenotypes of mast cells influence the susceptibility
to anaphylaxis, yet the mechanisms underlying proper maturation of mast cells toward an …

Among the emerging phospholipase A2 (PLA2) superfamily, the secreted PLA2 (sPLA2)
family consists of low-molecular-mass, Ca2+-requiring extracellular enzymes with a His-Asp …