Circulating tumor cell isolation for cancer diagnosis and prognosis

Z Deng, S Wu, Y Wang, D Shi - EBioMedicine, 2022 - thelancet.com
Circulating tumor cells (CTCs) are tumor cells that shed from the primary tumor and
intravasate into the peripheral blood circulation system responsible for metastasis. Sensitive …

Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Electrochemical methods for the analysis of clinically relevant biomolecules

M Labib, EH Sargent, SO Kelley - Chemical reviews, 2016 - ACS Publications
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …

Profiling circulating tumour cells and other biomarkers of invasive cancers

M Poudineh, EH Sargent, K Pantel… - Nature Biomedical …, 2018 - nature.com
During cancer progression, many tumours shed circulating tumour cells (CTCs) and other
biomarkers into the bloodstream. The analysis of CTCs offers the prospect of collecting a …

Tracking the dynamics of circulating tumour cell phenotypes using nanoparticle-mediated magnetic ranking

M Poudineh, PM Aldridge, S Ahmed, BJ Green… - Nature …, 2017 - nature.com
Profiling the heterogeneous phenotypes of rare circulating tumour cells (CTCs) in whole
blood is critical to unravelling the complex and dynamic properties of these potential clinical …

Nano-omics: nanotechnology-based multidimensional harvesting of the blood-circulating cancerome

L Gardner, K Kostarelos, P Mallick, C Dive… - Nature Reviews …, 2022 - nature.com
Over the past decade, the development of 'simple'blood tests that enable cancer screening,
diagnosis or monitoring and facilitate the design of personalized therapies without the need …

Manipulating cell fate: dynamic control of cell behaviors on functional platforms

W Li, Z Yan, J Ren, X Qu - Chemical Society Reviews, 2018 - pubs.rsc.org
The cell microenvironment choreographs the behaviors of cells through multiple well-
controlled signals. For basic biological study and cell-based therapies, it is essential to …

Microfluidic technologies for circulating tumor cell isolation

H Cho, J Kim, H Song, KY Sohn, MH Jeon, KH Han - Analyst, 2018 - pubs.rsc.org
Metastasis is the main cause of tumor-related death, and the dispersal of tumor cells through
the circulatory system is a critical step in the metastatic process. Early detection and analysis …

Recent advances in microfluidic platforms applied in cancer metastasis: Circulating tumor cells'(CTCs) isolation and tumor‐on‐a‐chip

Z Lin, G Luo, W Du, T Kong, C Liu, Z Liu - Small, 2020 - Wiley Online Library
Cancer remains the leading cause of death worldwide despite the enormous efforts that are
made in the development of cancer biology and anticancer therapeutic treatment …

Materials and microfluidics: enabling the efficient isolation and analysis of circulating tumour cells

JM Jackson, MA Witek, JW Kamande… - Chemical Society …, 2017 - pubs.rsc.org
We present a critical review of microfluidic technologies and material effects on the analyses
of circulating tumour cells (CTCs) selected from the peripheral blood of cancer patients …