A concise review of VEGF, PDGF, FGF, Notch, angiopoietin, and HGF signalling in tumor angiogenesis with a focus on alternative approaches and future directions

S Vimalraj - International Journal of Biological Macromolecules, 2022 - Elsevier
Angiogenesis forms new vessels from existing ones. Abnormal angiogenesis, which is what
gives tumor microenvironments their distinctive features, is characterised by convoluted …

Tumor-derived small extracellular vesicles in cancer invasion and metastasis: molecular mechanisms, and clinical significance

C Zhang, C Qin, S Dewanjee, H Bhattacharya… - Molecular Cancer, 2024 - Springer
The production and release of tumor-derived small extracellular vesicles (TDSEVs) from
cancerous cells play a pivotal role in the propagation of cancer, through genetic and …

The emerging role of 27-hydroxycholesterol in cancer development and progression: An update

SA Jasim, HH Kzar, MH Hamad, I Ahmad… - International …, 2022 - Elsevier
Oxysterols are cholesterol metabolites generated in the liver and other peripheral tissues as
a mechanism of removing excess cholesterol. Oxysterols have a wide range of biological …

The significant role of microRNAs in gliomas angiogenesis: a particular focus on molecular mechanisms and opportunities for clinical application

A Mafi, R Mannani, S Khalilollah, N Hedayati… - Cellular and Molecular …, 2023 - Springer
MicroRNAs (miRNAs) are non-coding RNAs with only 20–22 nucleic acids that inhibit gene
transcription and translation by binding to mRNA. MiRNAs have a diverse set of target genes …

Recent advances on high-efficiency of microRNAs in different types of lung cancer: a comprehensive review

MS Sadeghi, M Lotfi, N Soltani, E Farmani… - Cancer Cell …, 2023 - Springer
Carcinoma of the lung is among the most common types of cancer globally. Concerning its
histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer …

[HTML][HTML] Exosomal cargo: pro-angiogeneic, anti-inflammatory, and regenerative effects in ischemic and non-ischemic heart diseases–a comprehensive review

A Ahmadi, MG Ahmadabadi, A Babajani… - Biomedicine & …, 2023 - Elsevier
Heart diseases are the primary cause of mortality and morbidity worldwide which inflict a
heavy social and economic burden. Among heart diseases, most deaths are due to …

Exploring the potential of exosome-related LncRNA pairs as predictors for immune microenvironment, survival outcome, and microbiotain landscape in esophageal …

F Zhao, Z Li, Z Dong, Z Wang, P Guo… - Frontiers in …, 2022 - frontiersin.org
Accumulating studies have demonstrated the indispensable roles of exosomes and long
non-coding RNAs (lncRNAs) in cancer progression and the tumor microenvironment (TME) …

The role of microRNAs in multidrug resistance of glioblastoma

P Mahinfar, B Mansoori, D Rostamzadeh, B Baradaran… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma (GBM) is one of the most malignant types of central nervous
system tumor which accounts for more than 60% of all brain tumors in adults. Owing to poor …

Metabolic reprogramming by miRNAs in the tumor microenvironment: Focused on immunometabolism

SH Alshahrani, YS Ibrahim, AT Jalil, AA Altoum… - Frontiers in …, 2022 - frontiersin.org
MicroRNAs (miRNAs) are emerging as a significant modulator of immunity, and their
abnormal expression/activity has been linked to numerous human disorders, such as …

Antiangiogenic therapy for malignant brain tumors: does it still Matter?

A Pellerino, F Bruno, R Soffietti, R Rudà - Current Oncology Reports, 2023 - Springer
Abstract Purpose of Review To summarize the mechanisms of tumor angiogenesis and
resistance to antiangiogenic therapy, and the influence on tumor microenvironment. Recent …