Background Osteosarcopenia is a syndrome coexisting sarcopenia and osteopenia/
osteoporosis, with a high fracture risk. Recently, skeletal muscle and bone have been …

Rheumatoid arthritis (RA) is a systemic autoimmune disease that primarily affects the joints.
Organokines can produce beneficial or harmful effects in this condition. Among RA patients …

Irisin is a hormone-like myokine produced by the skeletal muscle in response to exercise.
Upon its release into the circulation, it is involved in the browning process and …

Objective This systematic review and meta-analysis aimed to investigate the association
between circulating irisin levels and osteoporosis in women, exploring irisin's potential role …

Rheumatoid arthritis (RA) is a chronic inflammatory disease manifested by joint involvement,
extra-articular manifestations, and general symptoms. Adipose tissue, previously perceived …

Irisin is a muscle factor induced by exercise, generated through the proteolytic cleavage of
the membrane protein fibronectin type III domain-containing protein 5 (FNDC-5). Numerous …

Background Lupus nephritis (LN) is a common presentation for systemic lupus
erythematosus (SLE) in rheumatology practice. SLE is associated with increased risk of …

Aim To elucidate the association of serum irisin levels with bone mineral density (BMD) and
calcium–phosphorus metabolism parameters in chronic kidney disease (CKD) patients and …

Base teórica. A ativação imune na artrite reumatoide (AR) gera uma inflamação sinovial
acentuada, levando à ativação de células estromais, como fibroblastos sinoviais (FLS), as …