Cell migration results from stepwise mechanical and chemical interactions between cells
and their extracellular environment. Mechanistic principles that determine single-cell and …

Mathematical and computational models can assist in gaining an understanding of cell
behavior at many levels of organization. Here, we review models in the literature that focus …

Oncolytic viruses are genetically engineered to treat growing tumours and represent a very
promising therapeutic strategy. Using a Gompertz growth law, we discuss a model that …

Collectively coordinated cell migration plays a role in tissue embryogenesis, cancer,
homeostasis and healing. To study these processes, different cell-based modelling …

Collective cell spreading takes place in spatially continuous environments, yet it is often
modelled using discrete lattice-based approaches. Here, we use data from a series of cell …

This review aims to propose the integrative implementation of microfluidic devices,
biomaterials, and computational methods that can lead to a significant progress in tissue …

Cell proliferation is the most important cellular-level mechanism responsible for regulating
cell population dynamics in living tissues. Modern experimental procedures show that the …

Quantifying the impact of biochemical compounds on collective cell spreading is an
essential element of drug design, with various applications including developing treatments …

Mechanical signals exist throughout the biological landscape. Across all scales, these
signals, in the form of force, stiffness, and deformations, are generated and processed …

Cell migration is essential in animal development, homeostasis, and disease progression,
but many questions remain unanswered about how this process is controlled. While many …