Cells in osteoclast and osteoblast lineages communicate with each other through cell–cell
contact, diffusible paracrine factors and cell–bone matrix interaction. Osteoclast–osteoblast …

Bone and the immune system are both complex tissues that respectively regulate the
skeleton and the body's response to invading pathogens. It has now become clear that these …

MicroRNAs regulated by lipopolysaccharide (LPS) target genes that contribute to the
inflammatory phenotype. Here, we showed that the protein kinase Akt1, which is activated by …

Patients with inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease,
are at increased risk of developing colon cancer, confirming that chronic inflammation …

After an acute ischemic stroke (AIS), inflammatory processes are able to concomitantly
induce both beneficial and detrimental effects. In this narrative review, we updated evidence …

Age‐related changes in human T‐cell populations are important contributors to
immunosenescence. In particular, terminally differentiated CD8+ effector memory CD45RA+ …

Objective: This study assessed gene expression by quantitative polymerase chain reaction
of inflammatory‐[interleukin (IL)‐12, tumor necrosis factor‐α (TNF‐α), IL‐4, and IL‐10] and …

Receptor activator of nuclear factor kappa B ligand (RANKL) and its natural antagonist,
osteoprotegerin (OPG), are, respectively, an indispensable factor and a potent inhibitor for …

Osteoprotegerin (OPG) is a soluble secreted protein and a decoy receptor, which inhibits a
receptor activator of nuclear factor κB (NF-κB) ligand (RANKL)/the receptor activator of NF …

One of the most sexually dimorphic aspects of metabolic regulation is the bidirectional
modulation of glucose homeostasis by testosterone in male and females. Severe …