The pathophysiology of neutrophilic dermatoses (NDs) and autoimmune connective tissue
diseases (AICTDs) is incompletely understood. The association between NDs and AICTDs …

Connective tissue disorders (CTD), which are often also termed collagen vascular diseases,
include a number of related inflammatory conditions. Some of these diseases include …

Pyoderma gangrenosum (PG) is an uncommon, distinctive cutaneous ulceration which is
usually idiopathic, but may be associated with many systemic disorders. The …

Pyoderma gangrenosum (PG) shows features of autoimmune and autoinlammatory
disorders. Genetic defects which afect the inlammasome, and in particular the NLRP3 zone …

Neutrophilic dermatoses, including S weet's syndrome, pyoderma gangrenosum, and
rheumatoid neutrophilic dermatitis, are inflammatory conditions of the skin often associated …

Leg ulcers are a manifestation of antiphospholipid syndrome (APS), and characteristically
respond poorly to treatment. Because the similar findings both clinical and pathological to …

Background Nonbullous neutrophilic dermatoses are seen infrequently in association with
lupus erythematosus (LE). A recently described histopathologic variant of Sweet syndrome …

Musculoskeletal manifestations involving the joints, muscle, bone, and supporting structures
are common in systemic lupus erythematosus (SLE) and can pose diagnostic and …

Pyoderma gangrenosum (PG) is an uncommon, idiopathic, ulcerative neutrophilic
dermatosis. It is characterized by painful nodular, bullous or pustular lesions that eventually …

Interventions: We found 23 previous cases of SLE and PG in the literature with most cases
(12/20) occurring during a lupus flare. Outcomes: Although rare, this association may be …