Multifunctional Cytochrome c: Learning New Tricks from an Old Dog

D Alvarez-Paggi, L Hannibal, MA Castro… - Chemical …, 2017 - ACS Publications
Cytochrome c (cyt c) is a small soluble heme protein characterized by a relatively flexible
structure, particularly in the ferric form, such that it is able to sample a broad conformational …

From synthesis to utilization: The ins and outs of mitochondrial heme

SA Swenson, CM Moore, JR Marcero, AE Medlock… - Cells, 2020 - mdpi.com
Heme is a ubiquitous and essential iron containing metallo-organic cofactor required for
virtually all aerobic life. Heme synthesis is initiated and completed in mitochondria, followed …

Down the iron path: mitochondrial iron homeostasis and beyond

JV Dietz, JL Fox, O Khalimonchuk - Cells, 2021 - mdpi.com
Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent.
Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate …

Molecular markers: a new paradigm in the prediction of sperm freezability

M Ďuračka, F Benko, E Tvrdá - International journal of molecular sciences, 2023 - mdpi.com
For decades now, sperm cryopreservation has been a pillar of assisted reproduction in
animals as well as humans. Nevertheless, the success of cryopreservation varies across …

Hydrogen-Bonded Supramolecular Nanotrap Enabling the Interfacial Activation of Hosted Enzymes

S Huang, J Li, Y Lin, L Tong, N Zhong… - Journal of the …, 2023 - ACS Publications
Engineering nanotraps to immobilize fragile enzymes provides new insights into designing
stable and sustainable biocatalysts. However, the trade-off between activity and stability …

Assembly of the complexes of the oxidative phosphorylation system in land plant mitochondria

EH Meyer, E Welchen, C Carrie - Annual Review of Plant …, 2019 - annualreviews.org
Plant mitochondria play a major role during respiration by producing the ATP required for
metabolism and growth. ATP is produced during oxidative phosphorylation (OXPHOS), a …

Complete mitochondrial genomes from the ferns Ophioglossum californicum and Psilotum nudum are highly repetitive with the largest organellar introns

W Guo, A Zhu, W Fan, JP Mower - New Phytologist, 2017 - Wiley Online Library
Currently, complete mitochondrial genomes (mitogenomes) are available from all major land
plant lineages except ferns. Sequencing of fern mitogenomes could shed light on the major …

[HTML][HTML] Sevoflurane induced neurotoxicity in neonatal mice links to a GSK3β/Drp1-dependent mitochondrial fission and apoptosis

J Liu, L Li, P Xie, X Zhao, D Shi, Y Zhang, C Pan… - Free Radical Biology and …, 2022 - Elsevier
Mitochondria damage and apoptosis were found associated with sevoflurane induced
neurotoxicity in developing brains of rodent and neuro cell lines. The detailed upstream …

Mitochondrial division inhibitor 1 (Mdivi-1) offers neuroprotection through diminishing cell death and improving functional outcome in a mouse model of traumatic brain …

Q Wu, SX Xia, QQ Li, Y Gao, X Shen, L Ma, MY Zhang… - Brain research, 2016 - Elsevier
Mitochondria dysfunction, an enormous potential crisis, has attracted increasing attention.
Disturbed regulation of mitochondrial dynamics, the balance of mitochondrial fusion and …

Incompatibility and interchangeability in molecular evolution

DB Sloan, JM Warren, AM Williams… - Genome Biology and …, 2023 - academic.oup.com
There is remarkable variation in the rate at which genetic incompatibilities in molecular
interactions accumulate. In some cases, minor changes—even single-nucleotide …