C yanotoxins: producing organisms, occurrence, toxicity, mechanism of action and human health toxicological risk evaluation

FM Buratti, M Manganelli, S Vichi, M Stefanelli… - Archives of …, 2017 - Springer
Cyanobacteria were present on the earth 3.5 billion years ago; since then they have
colonized almost all terrestrial and aquatic ecosystems. They produce a high number of …

Four decades of progress in cylindrospermopsin research: The ins and outs of a potent cyanotoxin

Y Yang, G Yu, Y Chen, N Jia, R Li - Journal of hazardous materials, 2021 - Elsevier
The cyanotoxin cylindrospermopsin (CYN), a toxic metabolite from cyanobacteria, is of
particular concern due to its cosmopolitan occurrence, aquatic bioaccumulation, and multi …

A comprehensive review: Development of electrochemical biosensors for detection of cyanotoxins in freshwater

V Vogiazi, A De La Cruz, S Mishra, V Shanov… - ACS …, 2019 - ACS Publications
Cyanobacteria harmful algal blooms are increasing in frequency and cyanotoxins have
become an environmental and public concern in the US and worldwide. In this Review, the …

In Vitro Toxicological Assessment of Cylindrospermopsin: A Review

S Pichardo, AM Cameán, A Jos - Toxins, 2017 - mdpi.com
Cylindrospermopsin (CYN) is a cyanobacterial toxin that is gaining importance, owing to its
increasing expansion worldwide and the increased frequency of its blooms. CYN mainly …

Mutagenic and genotoxic potential of pure Cylindrospermopsin by a battery of in vitro tests

M Puerto, AI Prieto, S Maisanaba… - Food and chemical …, 2018 - Elsevier
Cylindrospermopsin (CYN) is a cyanobacterial toxin with an increasing world-wide
occurrence. The main route of human exposure is through the ingestion of contaminated …

Cylindrospermopsin-microcystin-LR combinations may induce genotoxic and histopathological damage in rats

L Díez-Quijada, C Medrano-Padial… - Toxins, 2020 - mdpi.com
Cylindrospermopsin (CYN) and microcystins (MC) are cyanotoxins that can occur
simultaneously in contaminated water and food. CYN/MC-LR mixtures previously …

Application of advanced HepG2 3D cell model for studying genotoxic activity of cyanobacterial toxin cylindrospermopsin

K Hercog, M Štampar, A Štern, M Filipič… - Environmental pollution, 2020 - Elsevier
Cylindrospermopsin (CYN) is an emerging cyanotoxin increasingly being found in
freshwater cyanobacterial blooms worldwide. Humans and animals are exposed to CYN …

In vivo genotoxicity evaluation of cylindrospermopsin in rats using a combined micronucleus and comet assay

L Díez-Quijada, M Llana-Ruiz-Cabello… - Food and chemical …, 2019 - Elsevier
Cylindrospermopsin (CYN) is a potent cyanotoxin recognized as an emerging human threat
due to its cytotoxicity and potential carcinogenicity. Although the genotoxicity of CYN has …

Poly (ε-caprolactone) microspheres for prolonged release of selenium nanoparticles

N Filipović, L Veselinović, S Ražić, S Jeremić… - Materials Science and …, 2019 - Elsevier
Abstract Poly (ε-caprolactone)(PCL) microspheres as a carrier for sustained release of
antibacterial agent, selenium nanoparticles (SeNPs), were developed. The obtained …

Cytotoxic Effects and Oxidative Stress Produced by a Cyanobacterial Cylindrospermopsin Producer Extract versus a Cylindrospermopsin Non-Producing Extract on …

MG Hinojosa, A Cascajosa-Lira, AI Prieto… - Toxins, 2023 - mdpi.com
The incidence and interest of cyanobacteria are increasing nowadays because they are
able to produce some toxic secondary metabolites known as cyanotoxins. Among them, the …