Electrochemical methods for the analysis of clinically relevant biomolecules
Rapid progress in identifying biomarkers that are hallmarks of disease has increased
demand for high-performance detection technologies. Implementation of electrochemical …
demand for high-performance detection technologies. Implementation of electrochemical …
Signal amplification using functional nanomaterials for biosensing
J Lei, H Ju - Chemical Society Reviews, 2012 - pubs.rsc.org
Signal amplification based on biofunctional nanomaterials has recently attracted
considerable attention due to the need for ultrasensitive bioassays and the trend towards …
considerable attention due to the need for ultrasensitive bioassays and the trend towards …
Multivalent capture and detection of cancer cells with DNA nanostructured biosensors and multibranched hybridization chain reaction amplification
Sensitive detection of cancer cells plays a critically important role in the early detection of
cancer and cancer metastasis. However, because circulating tumor cells are extremely rare …
cancer and cancer metastasis. However, because circulating tumor cells are extremely rare …
Plasmonic cross-linking colorimetric PCR for simple and sensitive nucleic acid detection
Simple, low-cost, and accurate nucleic acid assay platforms hold great promise for point-of-
care (POC) pathogen detection, disease surveillance, and control. Plasmonic photothermal …
care (POC) pathogen detection, disease surveillance, and control. Plasmonic photothermal …
Homogeneous electrochemical strategy for human telomerase activity assay at single-cell level based on T7 exonuclease-aided target recycling amplification
X Liu, W Li, T Hou, S Dong, G Yu, F Li - Analytical chemistry, 2015 - ACS Publications
As an important biomarker for early cancer diagnostics and a valuable therapeutic target,
telomerase has attracted extensive attention concerning its detection and monitoring …
telomerase has attracted extensive attention concerning its detection and monitoring …
Platinum nanoparticles encapsulated metal–organic frameworks for the electrochemical detection of telomerase activity
A simple and rapid electrochemical sensor is constructed for the detection of telomerase
activity based on the electrocatalysis of platinum nanoparticle (Pt NP) encapsulated metal …
activity based on the electrocatalysis of platinum nanoparticle (Pt NP) encapsulated metal …
Visualizing human telomerase activity with primer‐modified Au nanoparticles
Telomerase is over‐expressed in over 85% of all known human tumors. This renders the
enzyme a valuable biomarker for cancer diagnosis and an important therapeutic target. The …
enzyme a valuable biomarker for cancer diagnosis and an important therapeutic target. The …
Real-time, quantitative lighting-up detection of telomerase in urines of bladder cancer patients by AIEgens
As a biomarker for early cancer diagnosis, telomerase are one of the promising targets for
cancer therapeutics. Inspired by the fluorescent emission principle of aggregation-induced …
cancer therapeutics. Inspired by the fluorescent emission principle of aggregation-induced …
Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe
A series of luminescent Ir (III) complexes were synthesised and evaluated for their ability to
act as G-quadruplex-selective probes. A novel Ir (III) complex was found to be highly …
act as G-quadruplex-selective probes. A novel Ir (III) complex was found to be highly …
Nucleic acid-driven aggregation-induced emission of Au nanoclusters for visualizing telomerase activity in living cells and in vivo
Visual monitoring of telomerase activity in living cancer cells and in vivo is essential for
clinical diagnosis and treatment. However, most detection methods were performed in vitro …
clinical diagnosis and treatment. However, most detection methods were performed in vitro …