Factors affecting antimicrobial resistance in Streptococcus pneumoniae following vaccination introduction

ER Watkins, A Kalizang'Oma, A Gori, S Gupta… - Trends in …, 2022 - cell.com
Streptococcus pneumoniae is a major cause of pneumonia, meningitis, and septicaemia
worldwide. Pneumococcal antimicrobial resistance (AMR) has been highlighted by the WHO …

Streptococcal peptides and their roles in host-microbe interactions

ER Wahlenmayer, DE Hammers - Frontiers in Cellular and Infection …, 2023 - frontiersin.org
The genus Streptococcus encompasses many bacterial species that are associated with
hosts, ranging from asymptomatic colonizers and commensals to pathogens with a …

Rgg-Shp regulators are important for pneumococcal colonization and invasion through their effect on mannose utilization and capsule synthesis

X Zhi, IT Abdullah, O Gazioglu, I Manzoor, S Shafeeq… - Scientific Reports, 2018 - nature.com
Microbes communicate with each other by using quorum sensing (QS) systems and
modulate their collective 'behavior'for in-host colonization and virulence, biofilm formation …

[HTML][HTML] Functional assessment of microbial superoxide dismutase isozymes suggests a differential role for each isozyme

H Najmuldeen, R Alghamdi, F Alghofaili… - Free radical biology and …, 2019 - Elsevier
Microbes can have multiple enzymes that are able to catalyse the same enzymatic reactions
but may differ in structure. These are known as isozymes. It is assumed that isozymes have …

A novel streptococcal cell–cell communication peptide promotes pneumococcal virulence and biofilm formation

RA Cuevas, R Eutsey, A Kadam… - Molecular …, 2017 - Wiley Online Library
Streptococcus pneumoniae (pneumococcus) is a major human pathogen. It is a common
colonizer of the human respiratory track, where it utilizes cell–cell communication systems to …

Environmental and genetic regulation of Streptococcus pneumoniae galactose catabolic pathways

BO Kareem, O Gazioglu, K Mueller Brown… - Nature …, 2024 - nature.com
Efficient utilization of nutrients is crucial for microbial survival and virulence. The same
nutrient may be utilized by multiple catabolic pathways, indicating that the physical and …

Function of BriC peptide in the pneumococcal competence and virulence portfolio

SD Aggarwal, R Eutsey, J West-Roberts… - PLoS …, 2018 - journals.plos.org
Streptococcus pneumoniae (pneumococcus) is an opportunistic pathogen that causes otitis
media, sinusitis, pneumonia, meningitis and sepsis. The progression to this pathogenic …

Puzzling over the pneumococcal pangenome

NL Hiller, R Sá-Leão - Frontiers in microbiology, 2018 - frontiersin.org
The Gram positive bacterium Streptococcus pneumoniae (pneumococcus) is a major human
pathogen. It is a common colonizer of the human host, and in the nasopharynx, sinus, and …

The pneumococcal social network

SD Aggarwal, H Yesilkaya, S Dawid, NL Hiller - PLoS Pathogens, 2020 - journals.plos.org
Gram-positive bacteria employ an array of secreted peptides to control population-level
behaviors in response to environmental cues. We review mechanistic and functional …

The Rgg1518 transcriptional regulator is a necessary facet of sugar metabolism and virulence in Streptococcus pneumoniae

B Shlla, O Gazioglu, S Shafeeq, I Manzoor… - Molecular …, 2021 - Wiley Online Library
Rggs are a group of transcriptional regulators with diverse roles in metabolism and
virulence. Here, we present work on the Rgg1518/SHP1518 quorum sensing system of …