Nonsense-mediated RNA decay (NMD) is a highly conserved RNA turnover pathway that
selectively degrades RNAs harbouring truncating mutations that prematurely terminate …

Nonsense-mediated RNA decay (NMD) was originally discovered as a cellular surveillance
pathway that safeguards the quality of mRNA transcripts in eukaryotic cells. In its canonical …

The variant curation guidelines published in 2015 by the American College of Medical
Genetics and Genomics and the Association for Molecular Pathology (ACMG/AMP) provided …

Background Long-read sequencing of full-length cDNAs enables the detection of structures
of aberrant splicing isoforms in cancer cells. These isoforms are occasionally translated …

Nonsense-mediated mRNA decay (NMD) is a conserved mRNA surveillance pathway that
cells use to ensure the quality of transcripts and to fine-tune transcript abundance. The role …

Nonsense-mediated decay (NMD) was first described as a quality-control mechanism that
targets and rapidly degrades aberrant mRNAs carrying premature termination codons …

Simple Summary Invasive lobular breast cancer (ILC) is a special type of breast cancer (BC)
that was first described in 1941. The diagnosis of ILC is made by microscopy of tumor …

NMD (nonsense-mediated mRNA decay) belongs to the best-studied mRNA surveillance
systems of the cell, limiting the synthesis of truncated and potentially harmful proteins on the …

The immensity of genes and molecules implicated in gastric carcinogenesis is
overwhelming and the relevant importance of some of these molecules is too often unclear …

Pancreatic adenosquamous carcinoma (ASC) is an enigmatic and aggressive tumor that
has a worse prognosis and higher metastatic potential than its adenocarcinoma counterpart …