Heart disease and stroke statistics—2023 update: a report from the American Heart Association

CW Tsao, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2023 - Am Heart Assoc
Background: The American Heart Association, in conjunction with the National Institutes of
Health, annually reports the most up-to-date statistics related to heart disease, stroke, and …

2024 heart disease and stroke statistics: a report of US and global data from the American Heart Association

SS Martin, AW Aday, ZI Almarzooq, CAM Anderson… - Circulation, 2024 - Am Heart Assoc
BACKGROUND: The American Heart Association (AHA), in conjunction with the National
Institutes of Health, annually reports the most up-to-date statistics related to heart disease …

Diagnosis and treatment of primary aldosteronism

M Reincke, I Bancos, P Mulatero, UI Scholl… - The lancet Diabetes & …, 2021 - thelancet.com
Primary aldosteronism is a common cause of secondary hypertension associated with
excess cardiovascular morbidities. Primary aldosteronism is underdiagnosed because it …

Aldosterone synthase inhibition with lorundrostat for uncontrolled hypertension: the target-HTN randomized clinical trial

LJ Laffin, D Rodman, JM Luther, A Vaidya, MR Weir… - Jama, 2023 - jamanetwork.com
Importance Excess aldosterone production contributes to hypertension in both classical
hyperaldosteronism and obesity-associated hypertension. Therapies that reduce …

Primary aldosteronism—a multidimensional syndrome

AF Turcu, J Yang, A Vaidya - Nature Reviews Endocrinology, 2022 - nature.com
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …

[HTML][HTML] Physiology, renin angiotensin system

JH Fountain, J Kaur, SL Lappin - 2017 - europepmc.org
The renin-angiotensin-aldosterone system (RAAS) is a critical regulator of blood volume,
electrolyte balance, and systemic vascular resistance. While the baroreceptor reflex …

Primary aldosteronism: state-of-the-art review

A Vaidya, GL Hundemer, K Nanba… - American Journal of …, 2022 - academic.oup.com
We are witnessing a revolution in our understanding of primary aldosteronism (PA). In the
past 2 decades, we have learned that PA is a highly prevalent syndrome that is largely …

Guideline-driven management of hypertension: an evidence-based update

RM Carey, JT Wright Jr, SJ Taler… - Circulation research, 2021 - Am Heart Assoc
Several important findings bearing on the prevention, detection, and management of
hypertension have been reported since publication of the 2017 American College of …

The role of mineralocorticoid receptor activation in kidney inflammation and fibrosis

JM Luther, AB Fogo - Kidney International Supplements, 2022 - Elsevier
Chronic kidney disease is characterized by progressive scarring that results in loss of
normal tissue in the kidney and eventually end-stage kidney disease. Interstitial fibrosis and …

Inequities in hypertension control in the United States exposed and exacerbated by COVID‐19 and the role of home blood pressure and virtual health care during and …

AP Bress, JB Cohen, DE Anstey, MB Conroy… - 2021 - Am Heart Assoc
The COVID‐19 pandemic is a public health crisis, having killed more than 514 000 US
adults as of March 2, 2021. COVID‐19 mitigation strategies have unintended consequences …