Opinion Statement The main purpose of the TNM system is to provide an anatomic-based
classification to adequately depict cancer prognosis. Accurate cancer staging is important for …

Importance To date, the magnitude of association and the quality of evidence for cutaneous
squamous cell carcinoma (cSCC) and risk factors for outcomes have not been reviewed and …

Cutaneous squamous cell carcinoma (cSCC) is the second most common form of human
cancer and has an increasing annual incidence. Although most cSCC is cured with office …

Purpose: Aggressive cutaneous squamous cell carcinoma (cSCC) is often a disfiguring and
lethal disease. Very little is currently known about the mutations that drive aggressive cSCC …

Non-melanoma skin cancer represents one-third of all malignancies and its incidence is
expected to rise until the year 2040. Cutaneous squamous cell carcinoma (cSCC) …

Importance Although most cases of cutaneous squamous cell carcinoma (CSCC) are easily
cured with surgery or ablation, a subset of these tumors recur, metastasize, and cause …

Background Cutaneous squamous-cell carcinomas (SCC) are among the most common
cancers capable of metastasis. Current Tumour Node Metastasis (TNM) staging includes …

Purpose To compare American Joint Committee on Cancer (AJCC), International Union
Against Cancer (UICC), and Brigham and Women's Hospital (BWH) tumor (T) staging …

Cutaneous squamous cell carcinoma (cSCC) is the second most common cancer, with its
incidence rising steeply. Immunosuppression is a well-established risk factor for cSCC, and …

Importance This study proposes an alternative tumor staging system for cutaneous
squamous cell carcinoma (CSCC) that more precisely defines the small subset of tumors …