Radiation therapy is a valuable tool in the treatment of numerous malignancies but, in
certain cases, can also causes significant acute and chronic damage to noncancerous …

Background Osteoradionecrosis of the jaws (ORNJ) is a severe and challenging
complication of head and neck radiation therapy. Despite its aggressiveness and …

Importance Patients with head and neck cancer undergo extraction of teeth with poor
prognoses to minimize post-radiation therapy (RT) extractions, which are known to cause …

ASCO Guidelines provide recommendations with comprehensive review and analyses of
the relevant literature for each recommendation, following the guideline development …

The emergence of new SARS-CoV-2 variants continues to pose an enormous public health
concern. The SARS-CoV-2 infection disrupted host immune response accounting for …

Background Treatment of osteoradionecrosis (ORN) is not a straightforward task, and it is
unpredictable. However, a combination of pentoxifylline; an antioxidant drug, and tocopherol …

Osteoradionecrosis (ORN) is described as a disease with exposed, nonviable bone that fails
to heal spontaneously or by means of conservative treatment after radiotherapy in at least 3 …

Purpose The aim of the present study was to determine the methodological quality of
systematic reviews that evaluated the effectiveness of pentoxifylline and tocopherol …

Patients treated for head and neck cancer may be susceptible to a higher incidence of
dental disease due to long-term sequelae of treatment for head and neck cancer. Most …

Objective Osteoradionecrosis (ORN) of the jaw is preceded by dental extractions in up to
10% of cases. We present a case series of post-radiotherapy patients undergoing dental …