This review addresses the ammonia fatigue theory in light of new evidence from exercise
and disease studies and aims to provide a view of the role of ammonia during exercise …

Critically-ill patients experience an extent of hyperinflammation, cellular immune
dysfunction, oxidative stress and mitochondrial dysfunction. Supplementation with key …

BACKGROUND/AIMS: Studies in acute liver failure show correlation between evidence of a
systemic inflammatory response syndrome (SIRS) and progression of hepatic …

Background: Minimal hepatic encephalopathy (MHE) is common in cirrhosis but its
pathophysiologic basis remains undefined. We evaluated whether the presence of MHE was …

The aim of the article is to examine side effects of increased dietary intake of amino acids,
which are commonly used as a dietary supplement. In addition to toxicity, mutagenicity and …

Objective: Spectral EEG analysis has been claimed to reduce subjective variability in EEG
assessment of hepatic encephalopathy and to allow the detection of mild encephalopathy …

There is no “gold standard” for diagnosing hepatic encephalopathy in patients with cirrhosis.
In consequence, the presence of this condition, unless floridly overt, is often missed. As a …

Hepatic encephalopathy (HE) is a serious neuropsychiatric and neurocognitive complication
of acute and chronic liver disease. Symptoms are often overt (confusion, disorientation …

Some people consume chronically glutamine (GLN) in high quantities (~ 40 g/d), although a
number of biochemical pathways and cellular functions may be negatively affected. The …

Hepatic encephalopathy (HE) is a decline in brain function arising due to liver insufficiency.
The liver's diminished capacity to clear ammonia, and the subsequent accumulation of it, is …