Gastric cancer: where are we heading?

P Petryszyn, N Chapelle, T Matysiak-Budnik - Digestive Diseases, 2020 - karger.com
Background: Despite its decreasing incidence, gastric cancer (GC) remains one of the
leading cancers in the world and an important global healthcare problem due to its overall …

[HTML][HTML] Small extracellular vesicles in cancer

K Abhange, A Makler, Y Wen, N Ramnauth, W Mao… - Bioactive Materials, 2021 - Elsevier
Extracellular vesicles (EV) are lipid-bilayer enclosed vesicles in submicron size that are
released from cells. A variety of molecules, including proteins, DNA fragments, RNAs, lipids …

DNA methylation as a molecular biomarker in gastric cancer

T Tahara, T Arisawa - Epigenomics, 2015 - Taylor & Francis
DNA methylation plays a significant role in gastric carcinogenesis. The CpG island
methylator phenotype (CIMP) characterizes distinct subtypes of gastric cancer (GC) and the …

The role of SOX family transcription factors in gastric cancer

AJ Abadi, A Zarrabi, F Hashemi, A Zabolian… - International journal of …, 2021 - Elsevier
Gastric cancer (GC) is a leading cause of death worldwide. GC is the third-most common
cause of cancer-related death after lung and colorectal cancer. It is also the fifth-most …

Biomarkers for gastric cancer: Progression in early diagnosis and prognosis

Z Jin, W Jiang, L Wang - Oncology letters, 2015 - spandidos-publications.com
Gastric cancer is one of leading causes of cancer‑related mortality worldwide and is a
notable disease due to its heterogeneity. Recently, numerous studies have investigated the …

The role of extracellular vesicles: an epigenetic view of the cancer microenvironment

Z Qian, Q Shen, X Yang, Y Qiu… - BioMed research …, 2015 - Wiley Online Library
Exosomes, microvesicles, and other extracellular vesicles are released by many cell types,
including cancer cells and cancer‐related immune cells. Extracellular vesicles can directly …

Aberrantly hypermethylated tumor suppressor genes were identified in oral squamous cell carcinoma (OSCC)

SY Kim, YK Han, JM Song, CH Lee, K Kang, JM Yi… - Clinical …, 2019 - Springer
Background Oral squamous cell carcinoma (OSCC) is a genetic and epigenetic disease.
There is growing evidence to suggest that environmental factors due to epigenetic changes …

BARHL2Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in anH. pylori-Independent …

H Yamamoto, Y Watanabe, R Oikawa… - Clinical and …, 2016 - journals.lww.com
OBJECTIVES: The main purpose of this study was to develop a methylation analysis
pipeline by using gastric wash-derived DNA and/or gastric juice-derived exosomal DNA …

Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression

IY Kuo, CC Wu, JM Chang, YL Huang… - … journal of cancer, 2014 - Wiley Online Library
The transcriptional network of the SRY (sex determining region Y)‐box 17 (SOX17) and the
prognostic impact of SOX17 protein expression in human cancers remain largely unclear. In …

MiRNA‐199a‐3p: A potential circulating diagnostic biomarker for early gastric cancer

C Li, JF Li, Q Cai, QQ Qiu, M Yan… - Journal of surgical …, 2013 - Wiley Online Library
Background Tumor‐associated miRNAs have been detected in serum or plasma. We
investigated whether plasma miRNA‐199a‐3p could be a potential circulating biomarker for …