Stroke is the second leading cause of death and a major contributor to disability worldwide.
The prevalence of stroke is highest in developing countries, with ischemic stroke being the …

The vast majority of cerebral stroke cases are caused by transient or permanent occlusion of
a cerebral blood vessel (“ischemic stroke”) eventually leading to brain infarction. The final …

This review outlines the most frequently used rodent stroke models and discusses their
strengths and shortcomings. Mimicking all aspects of human stroke in one animal model is …

Rodent stroke models provide the experimental backbone for the in vivo determination of the
mechanisms of cell death and neural repair, and for the initial testing of neuroprotective …

Animal models of stroke provide an essential tool for the understanding of the complex
cellular and molecular pathophysiology of stroke and for testing novel recanalyzing …

Background and Purpose—Brain edema is a life-threatening consequence of stroke and
leads to an extension of the affected tissue. The space-occupying effect due to brain edema …

Stroke is one of the major healthcare challenges prevailing across the globe due to its
significant rate of mortality and morbidity. Stroke is multifactorial in nature and involves …

Astaxanthin (AST) is a powerful antioxidant that occurs naturally in a wide variety of living
organisms. Much experimental evidence has proved that AST has the function of eliminating …

Introduction: Representing the leading cause of long-term disability, ischemic stroke urgently
needs further research and drug development. This review summarizes current animal …

Ischemic diseases, the leading cause of disability and death, are caused by the restriction or
blockage of blood flow in specific tissues, including ischemic cardiac, ischemic …