The burnt-bridges ratchet (BBR) mechanism is a model for biased molecular motion
whereby the construct destroys track binding sites as it progresses and therefore acts as a …

We propose and analyze a mathematical model of cargo transport by nonprocessive
molecular motors. In our model, the motors change states by random discrete events …

Analytical formulas for effective drift, diffusivity, run times, and run lengths are derived for an
intracellular transport system consisting of a cargo attached to two cooperative but not …

We examine the localization patterns of ParA, ParB, PopZ, and MipZ, which are key division
proteins in C. crescentus bacteria. While Par and PopZ proteins have been implicated in the …

In many biological systems, the movement of individual agents is characterized having
multiple qualitatively distinct behaviors that arise from a variety of biophysical states. For …

We develop a multi-method sensitivity framework, which incorporates two variance-based
methods, namely Sobol's method, eFAST and Derivative-based global measures to identify …