Engineering magnetic extracellular vesicles mimetics for enhanced targeting chemodynamic therapy to overcome ovary cancer
S Wang, Y Mao, S Rong, G Liu, Y Cao… - … Applied Materials & …, 2024 - ACS Publications
Chemodynamic therapy (CDT), employing metal ions to transform endogenous H2O2 into
lethal hydroxyl radicals (• OH), has emerged as an effective approach for tumor treatment …
lethal hydroxyl radicals (• OH), has emerged as an effective approach for tumor treatment …
Triggering multiple modalities of cell death via dual-responsive nanomedicines to address the narrow therapeutic window of β-lapachone
F Liu, Y Li, Y Li, Z Wang, X Li, Y Liu, Y Zhao - Journal of Colloid and …, 2025 - Elsevier
The clinical translation of the anticancer drug β-lapachone (LAP) has been limited by the
narrow therapeutic window. Stimuli-responsive anticancer drug delivery systems have …
narrow therapeutic window. Stimuli-responsive anticancer drug delivery systems have …
An azo bond primary cleavage and C–C bond secondary cleavage-based polymeric β-lapachone prodrug for selective anti-cancer therapy
W Zhao, M Zheng, H Chu, J Zhang, K Wang… - Science China …, 2025 - Springer
ABSTRACT β-Lapachone (β-Lap) is a promising ortho-naphthoquinone drug for cancer
treatment and has been in clinical trials. Its application is constrained by the low aqueous …
treatment and has been in clinical trials. Its application is constrained by the low aqueous …
NAD (P) H-quinone oxidoreductase 1 induces complicated effects on mitochondrial dysfunction and ferroptosis in an expression level-dependent manner
J Lee, DH Hyun - BioScience Trends, 2024 - jstage.jst.go.jp
NAD (P) H-quinone oxidoreductase 1 (NQO1) is an essential redox enzyme responsible for
redox balance and energy metabolism. Despite of its importance, the brain contains high …
redox balance and energy metabolism. Despite of its importance, the brain contains high …
Pools of independently cycling inositol phosphates revealed by pulse labeling with 18O-water
Inositol phosphates control many central processes in eukaryotic cells, including nutrient
availability, growth, and motility. Kinetic resolution of a key modulator of their signaling …
availability, growth, and motility. Kinetic resolution of a key modulator of their signaling …
[PDF][PDF] Induction of Apoptosis by β-Lapachone in Hep3B Human Hepatocellular Carcinoma Cells Is Caspase-Dependent and Associated with Inactivation of PI3K/Akt …
J Im Kwon, YH Choi, H Hwangbo - Journal of Life Science, 2024 - koreascience.kr
Revised February 1, 2024/Accepted February 1, 2024 β-Lapachone is a natural quinone
compound originally obtained from the bark of the lapacho tree (Tabebuia vellanedae) …
compound originally obtained from the bark of the lapacho tree (Tabebuia vellanedae) …
Hep3B 인간간암세포에서caspase 의존적이며PI3K/Akt 신호전달의불활성화와관련된β-lapachone 의세포사멸유도
권재임， 최영현， 황보현 - 생명과학회지, 2024 - dbpia.co.kr
β-lapachone 은 다양한 유형의 질병을 치료하기 위해 남미 및 중미 지역의 전통 의학에서 널리
사용되어온 Tabebuia vellanedae 의 껍질에서 분리된 천연 퀴논 화합물의 일종이다. β …
사용되어온 Tabebuia vellanedae 의 껍질에서 분리된 천연 퀴논 화합물의 일종이다. β …