Pathogenesis of HIV-related lung disease: immunity, infection, and inflammation

SK Cribbs, K Crothers, A Morris - Physiological reviews, 2020 - journals.physiology.org
Despite anti-retroviral therapy (ART), human immunodeficiency virus-1 (HIV)-related
pulmonary disease continues to be a major cause of morbidity and mortality for people living …

HIV and chronic obstructive pulmonary disease: is it worse and why?

A Morris, MP George, K Crothers, L Huang… - Proceedings of the …, 2011 - atsjournals.org
Smoking-related diseases, such as chronic obstructive pulmonary disease (COPD), are of
particular concern in the HIV-infected population. Smoking rates are high in this population …

Chronic obstructive pulmonary disease: an emerging comorbidity in HIV-infected patients in the HAART era?

G Madeddu, AG Fois, GM Calia, S Babudieri, V Soddu… - Infection, 2013 - Springer
Purpose The objective of our study was to evaluate the presence of respiratory symptoms
and chronic obstructive pulmonary disease (COPD) in a human immunodeficiency virus …

Association between obstructive lung disease and markers of HIV infection in a high-risk cohort

MB Drummond, GD Kirk, J Astemborski, MM Marshall… - Thorax, 2012 - thorax.bmj.com
Background Evidence suggests an association between HIV infection and the presence of
obstructive lung disease (OLD). However, the associations between specific markers of HIV …

HIV associated pulmonary emphysema: a review of the literature and inquiry into its mechanism

I Petrache, K Diab, KS Knox, HL Twigg, RS Stephens… - Thorax, 2008 - thorax.bmj.com
Chronic lung diseases are increasingly recognised complications of the human
immunodeficiency virus (HIV) infection and acquired immune deficiency syndrome (AIDS) …

Effects of smoking on non-AIDS-related morbidity in HIV-infected patients

DK Shirley, RJ Kaner, MJ Glesby - Clinical infectious diseases, 2013 - academic.oup.com
Tobacco smoking has many adverse health consequences. Patients with human
immunodeficiency virus (HIV) infection smoke at very high rates, and many of the …

The lungs as anatomical reservoirs of HIV infection

CT Costiniuk, MA Jenabian - Reviews in medical virology, 2014 - Wiley Online Library
Failure of antiretroviral therapy to eradicate HIV, even in individuals who suppress the virus
to undetectable levels, is a consequence of persistent infection in latently infected cells and …

Effect of cigarette smoking on HIV acquisition, progression, and mortality

MM Marshall, MC McCormack, GD Kirk - AIDS Education and …, 2009 - Guilford Press
Cigarette smoking is more common among those with HIV compared with the general
population. However, it remains unclear whether smoking alters the natural history of HIV …

The complexity of HIV persistence and pathogenesis in the lung under antiretroviral therapy: challenges beyond AIDS

S Almodovar - Viral immunology, 2014 - liebertpub.com
Antiretroviral therapy (ART) represents a significant milestone in the battle against AIDS.
However, we continue learning about HIV and confronting challenges 30 years after its …

Activation-induced Cell Death Drives Profound Lung CD4+ T-Cell Depletion in HIV-associated Chronic Obstructive Pulmonary Disease

I Popescu, MB Drummond, L Gama, T Coon… - American journal of …, 2014 - atsjournals.org
Rationale: As overall survival improves, individuals with HIV infection become susceptible to
other chronic diseases, including accelerated chronic obstructive pulmonary disease …