Central nervous system (CNS) diseases threaten the health of people all over the world.
However, due to the structural and functional particularities of the brain and spinal cord …

Glioblastoma (GBM) is the most common intrinsic and aggressive primary brain tumor in
adults, with a median survival of approximately 15 months. GBM heterogeneity is considered …

The homeostasis of bone microenvironment is the foundation of bone health and comprises
2 concerted events: bone formation by osteoblasts and bone resorption by osteoclasts. In …

Despite significant advances in the understanding of cancer biology, cancer is still a leading
cause of death worldwide. Expression of the tumor microenvironment component …

Abstract Brain-Machine Interface systems (BMIs) are clinically valuable devices that can
provide functional restoration for patients with spinal cord injury or improved integration for …

Breast cancer is a common malignancy in women with poor prognosis. This study aimed to
investigate the molecular mechanism of microRNA-944 (miR-944) mediated secreted …

The autoimmune diseases of the central nervous system (CNS) represent individual
heterogeneity with different disease entities. Although clinical and imaging features make it …

Introduction Neuroinflammation plays an important role in the development of major
depressive disorder (MDD). Osteopontin (OPN) is one of the key molecules involved in …

Background Diffuse large B-cell lymphoma (DLBCL) is an aggressive malignancy.
Neutrophil extracellular traps (NETs) are pathogen-trapping structures in the tumor …

Genomic profiling in postmortem brain from autistic individuals has consistently revealed
convergent molecular changes. What drives these changes and how they relate to genetic …