Sialic acid–binding immunoglobulin-type lectins (Siglecs) are expressed on the majority of
white blood cells of the immune system and play critical roles in immune cell signaling …

While membrane models now include the heterogeneous distribution of lipids, the impact of
membrane charges on regulating the association of proteins with the plasma membrane is …

Diverse cellular signaling events, including B cell receptor (BCR) activation, are
hypothesized to be facilitated by domains enriched in specific plasma membrane lipids and …

S-palmitoylation is a reversible, enzymatic posttranslational modification of proteins in which
palmitoyl chain is attached to a cysteine residue via a thioester linkage. S-palmitoylation …

Since the cloning of the critical adapter, LAT (linker for activation of T cells), more than 15
years ago, a combination of multiple scientific approaches and techniques continues to …

The sialic acid-binding immunoglobulin-type of lectins (Siglecs) are receptors that recognize
sialic acid-containing glycans. In the majority of the cases, Siglecs are expressed on …

Glycolipids are glycoconjugates that are predominantly found on the extracellular surface of
cells ranging from bacteria to men. In bacteria and plants, glycoglycerolipids represent the …

Flotillin-1 and flotillin-2 are ubiquitously expressed, membrane-associated proteins involved
in multifarious cellular events from cell signaling, endocytosis, and protein trafficking to gene …

Transforming growth factor β (TGF-β) is a pleiotropic cytokine expressed by a wide range of
cell types and is known for hampering the effectiveness of cancer immune cell therapeutic …

More than one million new cases of breast cancer are diagnosed worldwide each year and
more than 400,000 deaths are caused by the disease. The origin of this pathology is …