Melanoma

D Schadendorf, DE Fisher, C Garbe… - Nature reviews Disease …, 2015 - nature.com
Melanoma is a common cancer in the Western world with an increasing incidence. Sun
exposure is still considered to be the major risk factor for melanoma. The prognosis of …

Biology of melanoma

SM Ostrowski, DE Fisher - Hematology/Oncology Clinics, 2021 - hemonc.theclinics.com
Melanoma skin cancer is derived from skin melanocytes and has a high risk of metastatic
spread. Many clinical attributes and risk factors associated with melanoma have been well …

Rate of diagnostic errors and serious misdiagnosis-related harms for major vascular events, infections, and cancers: toward a national incidence estimate using the “ …

DE Newman-Toker, Z Wang, Y Zhu, N Nassery… - Diagnosis, 2021 - degruyter.com
Background Missed vascular events, infections, and cancers account for~ 75% of serious
harms from diagnostic errors. Just 15 diseases from these “Big Three” categories account for …

Recognising skin cancer in primary care

OT Jones, CKI Ranmuthu, PN Hall, G Funston… - Advances in …, 2020 - Springer
Skin cancer, including melanoma, basal cell carcinoma and cutaneous squamous cell
carcinoma, has one of the highest global incidences of any form of cancer. In 2016 more …

Association between NRAS and BRAF mutational status and melanoma-specific survival among patients with higher-risk primary melanoma

NE Thomas, SN Edmiston, A Alexander… - JAMA …, 2015 - jamanetwork.com
Importance NRASandBRAFmutations in melanoma inform current treatment paradigms, but
their role in survival from primary melanoma has not been established. Identification of …

Amelanotic melanoma

HZ Gong, HY Zheng, J Li - Melanoma research, 2019 - journals.lww.com
Cutaneous amelanotic melanoma (AM) is a rare amelanotic or a hypomelanotic subtype of
melanoma, comprising only 0.4–27.5% of all melanoma cases. The mean age of the …

Oxidative stress in melanogenesis and melanoma development

K Kamiński, U Kazimierczak, T Kolenda - Contemporary Oncology …, 2022 - termedia.pl
Melanoma is the most aggressive skin cancer, with a growing number of incidents
worldwide and with no effective cure in a metastatic stage so far. There are several …

Current molecular markers of melanoma and treatment targets

K Yang, ASW Oak, RM Slominski, AA Brożyna… - International journal of …, 2020 - mdpi.com
Melanoma is a deadly skin cancer that becomes especially difficult to treat after it
metastasizes. Timely identification of melanoma is critical for effective therapy, but …

Melanin presence inhibits melanoma cell spread in mice in a unique mechanical fashion

M Sarna, M Krzykawska-Serda, M Jakubowska… - Scientific reports, 2019 - nature.com
Melanoma is a highly aggressive cancer that exhibits metastasis to various critical organs.
Unlike any other cancer cells, melanoma cells can synthesize melanin in large amounts …

Clinical advances and perspectives in targeted radionuclide therapy

N Lepareur, B Ramée, M Mougin-Degraef… - Pharmaceutics, 2023 - mdpi.com
Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine
subspecialty. For many decades, treatment with radionuclides has been mainly restricted to …