IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Neurodevelopmental resilience and susceptibility to maternal immune activation

U Meyer - Trends in neurosciences, 2019 - cell.com
Maternal immune activation (MIA), be it triggered by infectious or noninfectious stimuli, is
implicated in various psychiatric and neurological disorders with developmental etiologies …

Targeting cannabinoid signaling in the immune system:“High”-ly exciting questions, possibilities, and challenges

A Oláh, Z Szekanecz, T Bíró - Frontiers in Immunology, 2017 - frontiersin.org
It is well known that certain active ingredients of the plants of Cannabis genus, ie, the
“phytocannabinoids”[pCBs; eg,(−)-trans-Δ9-tetrahydrocannabinol (THC),(−)-cannabidiol …

THC and CBD: villain versus hero? Insights into adolescent exposure

N Pintori, F Caria, MA De Luca, C Miliano - International Journal of …, 2023 - mdpi.com
Cannabis is the most used drug of abuse worldwide. It is well established that the most
abundant phytocannabinoids in this plant are Δ9-tetrahydrocannabinol (THC) and …

Inflammatory markers in substance use and mood disorders: a neuroimaging perspective

K Agarwal, P Manza, M Chapman, N Nawal… - Frontiers in …, 2022 - frontiersin.org
Chronic exposure to addictive drugs in substance use disorders and stressors in mood
disorders render the brain more vulnerable to inflammation. Inflammation in the brain, or …

Inflammatory biomarkers in addictive disorders

A Morcuende, F Navarrete, E Nieto, J Manzanares… - Biomolecules, 2021 - mdpi.com
Substance use disorders are a group of diseases that are associated with social,
professional, and family impairment and that represent a high socio-economic impact on the …

Pro-inflammatory cytokines: potential links between the endocannabinoid system and the kynurenine pathway in depression

F Zádor, S Joca, G Nagy-Grócz, S Dvorácskó… - International journal of …, 2021 - mdpi.com
Substance use/abuse is one of the main causes of depressive symptoms. Cannabis and
synthetic cannabinoids in particular gained significant popularity in the past years. There is …

Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder

DC D'Souza, R Radhakrishnan, M Naganawa… - Molecular …, 2021 - nature.com
Cannabis is one of the most commonly and widely used psychoactive drugs. The rates of
cannabis misuse have been increasing. Therefore, understanding the effects of cannabis …

The long-term cognitive consequences of adolescent exposure to recreational drugs of abuse

SM Mooney-Leber, TJ Gould - Learning & memory, 2018 - learnmem.cshlp.org
During adolescence, the brain continues to undergo vital developmental processes. In turn,
complex behavioral and cognitive skills emerge. Unfortunately, neurobiological …

Stress-and drug-induced neuroimmune signaling as a therapeutic target for comorbid anxiety and substance use disorders

CE Smiley, SK Wood - Pharmacology & therapeutics, 2022 - Elsevier
Stress and substance use disorders remain two of the most highly prevalent psychiatric
conditions and are often comorbid. While individually these conditions have a debilitating …