Macrophages are pivotal cells involved in chronic inflammatory and autoimmune diseases.
In fact, during these diseases, activated macrophages may play a critical role, promoting the …

Mesenchymal stromal/stem cells (MSC) are non-hematopoietic multipotent progenitor cells,
first described in bone marrow in the middle of last century. Since then, MSC have been the …

Background In patients with systemic sclerosis (scleroderma, SSc), impaired hand function
greatly contributes to disability and reduced quality of life, and is insufficiently relieved by …

Systemic sclerosis (SSc or scleroderma) is a progressive and highly debilitating
autoimmune disorder characterized by inflammation, vasculopathy, and extensive fibrosis …

Systemic sclerosis (SSc) is a rare chronic autoimmune disease characterized by
vasculopathy, dysregulation of innate and adaptive immune responses, and progressive …

Background A randomized controlled trial (RCT) was performed to confirm preliminary
uncontrolled data indicating that regional adipose tissue (AT) grafting (G) is effective in …

Systemic sclerosis (SSc) is an autoimmune disease characterized by significant vascular
alterations and multi-organ fibrosis. Microvascular alterations are the first event of SSc and …

Systemic sclerosis (SSc) is an intractable autoimmune disease with unmet medical needs.
Conventional immunosuppressive therapies have modest efficacy and obvious side effects …

There is increasing evidence that mesenchymal stem cells (MSCs) have the ability to
migrate and engraft into tumor sites and exert stimulatory effects on cancer cell growth …

Ferritin is an iron-binding molecule, which comprises 24 subunits, heavy (FeH) and light
(FeL) subunits, suggested to have a pathogenic role by the 'hyperferritinemic syndrome'. In …