The role of inflammation in irritable bowel syndrome (IBS)

QX Ng, AYS Soh, W Loke, DY Lim… - Journal of inflammation …, 2018 - Taylor & Francis
Irritable bowel syndrome (IBS) is a complex, functional gastrointestinal disorder
characterized by chronic abdominal pain or discomfort and altered bowel habits. Despite the …

Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis

AC Ford, EMM Quigley, BE Lacy… - Official journal of the …, 2014 - journals.lww.com
OBJECTIVES: Irritable bowel syndrome (IBS) and chronic idiopathic constipation (CIC) are
functional bowel disorders. Evidence suggests that disturbance in the gastrointestinal …

Crosstalk between muscularis macrophages and enteric neurons regulates gastrointestinal motility

PA Muller, B Koscsó, GM Rajani, K Stevanovic… - Cell, 2014 - cell.com
Intestinal peristalsis is a dynamic physiologic process influenced by dietary and microbial
changes. It is tightly regulated by complex cellular interactions; however, our understanding …

The role of mast cells in functional GI disorders

MM Wouters, M Vicario, J Santos - Gut, 2016 - gut.bmj.com
Functional gastrointestinal disorders (FGIDs) are characterized by chronic complaints
arising from disorganized brain-gut interactions leading to dysmotility and hypersensitivity …

[HTML][HTML] Extra-intestinal and long term consequences of Giardia duodenalis infections

MCM Halliez, AG Buret - World journal of gastroenterology: WJG, 2013 - ncbi.nlm.nih.gov
Giardiasis is the most common waterborne parasitic infection of the human intestine
worldwide. The etiological agent, Giardia duodenalis (syn. G. intestinalis, G. lamblia), is a …

The enteric nervous system in gastrointestinal disease etiology

AM Holland, AC Bon-Frauches, D Keszthelyi… - Cellular and Molecular …, 2021 - Springer
A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …

Activated mast cells in proximity to colonic nerves correlate with abdominal pain in irritable bowel syndrome

G Barbara, V Stanghellini, R De Giorgio, C Cremon… - Gastroenterology, 2004 - Elsevier
Background & Aims: The mechanisms underlying abdominal pain perception in irritable
bowel syndrome (IBS) are poorly understood. Intestinal mast cell infiltration may perturb …

Lactobacillus and bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine profiles

L O'Mahony, J McCarthy, P Kelly, G Hurley, F Luo… - Gastroenterology, 2005 - Elsevier
Background&Aims: The aim of this study was to compare the response of symptoms and
cytokine ratios in irritable bowel syndrome (IBS) with ingestion of probiotic preparations …

Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation

M Vivinus-Nébot, G Frin-Mathy, H Bzioueche… - Gut, 2014 - gut.bmj.com
Objective To determine the role of colonic barrier defects and low-grade inflammation in
irritable bowel syndrome (IBS)-like symptoms in quiescent inflammatory bowel disease …

[HTML][HTML] Advances in the diagnosis and classification of gastric and intestinal motility disorders

J Keller, G Bassotti, J Clarke, P Dinning… - Nature reviews …, 2018 - nature.com
Disturbances of gastric, intestinal and colonic motor and sensory functions affect a large
proportion of the population worldwide, impair quality of life and cause considerable health …