Anatomy, Function, and Dysfunction of the Right Ventricle: JACC State-of-the-Art Review
J Sanz, D Sánchez-Quintana, E Bossone… - Journal of the American …, 2019 - jacc.org
There is increasing recognition of the crucial role of the right ventricle (RV) in determining
functional status and prognosis in multiple conditions. The normal RV is anatomically and …
functional status and prognosis in multiple conditions. The normal RV is anatomically and …
The relationship between the right ventricle and its load in pulmonary hypertension
A Vonk Noordegraaf, BE Westerhof… - Journal of the American …, 2017 - jacc.org
In pulmonary hypertension, the right ventricle adapts to the increasing vascular load by
enhancing contractility (“coupling”) to maintain flow. Ventriculoarterial coupling implies that …
enhancing contractility (“coupling”) to maintain flow. Ventriculoarterial coupling implies that …
Assessment of right ventricular function in the research setting: knowledge gaps and pathways forward. An Official American Thoracic Society Research Statement
Background: Right ventricular (RV) adaptation to acute and chronic pulmonary hypertensive
syndromes is a significant determinant of short-and long-term outcomes. Although …
syndromes is a significant determinant of short-and long-term outcomes. Although …
Imaging of pulmonary hypertension in adults: a position paper from the Fleischner Society
M Remy-Jardin, CJ Ryerson, ML Schiebler… - Radiology, 2021 - pubs.rsna.org
Pulmonary hypertension (PH) is defined by a mean pulmonary artery pressure greater than
20 mm Hg and classified into five different groups sharing similar pathophysiologic …
20 mm Hg and classified into five different groups sharing similar pathophysiologic …
The right ventricle in pulmonary arterial hypertension: disorders of metabolism, angiogenesis and adrenergic signaling in right ventricular failure
The right ventricle (RV) is the major determinant of functional state and prognosis in
pulmonary arterial hypertension. RV hypertrophy (RVH) triggered by pressure overload is …
pulmonary arterial hypertension. RV hypertrophy (RVH) triggered by pressure overload is …
Right ventricular adaptation and failure in pulmonary arterial hypertension
Pulmonary arterial hypertension (PAH) is an obstructive pulmonary vasculopathy,
characterized by excess proliferation, apoptosis resistance, inflammation, fibrosis, and …
characterized by excess proliferation, apoptosis resistance, inflammation, fibrosis, and …
Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI)
Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it
remains a life-shortening condition. There have been significant advances in imaging …
remains a life-shortening condition. There have been significant advances in imaging …
Emerging concepts in the molecular basis of pulmonary arterial hypertension: part I: metabolic plasticity and mitochondrial dynamics in the pulmonary circulation and …
Mitochondria are central to cellular metabolism. The metabolic pathways of mitochondria
include fatty acid oxidation, glucose oxidation, and glutaminolysis. The initial step in glucose …
include fatty acid oxidation, glucose oxidation, and glutaminolysis. The initial step in glucose …
Systemic sclerosis-associated pulmonary arterial hypertension
NF Chaisson, PM Hassoun - Chest, 2013 - Elsevier
Pulmonary arterial hypertension (PAH) is the leading cause of death in systemic sclerosis
(SSc) and affects up to 12% of all patients with SSc, with a 50% mortality rate within 3 years …
(SSc) and affects up to 12% of all patients with SSc, with a 50% mortality rate within 3 years …
Metabolism and bioenergetics in the right ventricle and pulmonary vasculature in pulmonary hypertension
Pulmonary arterial hypertension (PAH) is a syndrome in which pulmonary vascular cross
sectional area and compliance are reduced by vasoconstriction, vascular remodeling, and …
sectional area and compliance are reduced by vasoconstriction, vascular remodeling, and …