Current trends in computer aided drug design and a highlight of drugs discovered via computational techniques: A review

VT Sabe, T Ntombela, LA Jhamba… - European Journal of …, 2021 - Elsevier
Computer-aided drug design (CADD) is one of the pivotal approaches to contemporary pre-
clinical drug discovery, and various computational techniques and software programs are …

Structural basis of potential inhibitors targeting SARS-CoV-2 main protease

HM Mengist, T Dilnessa, T Jin - Frontiers in Chemistry, 2021 - frontiersin.org
The Coronavirus disease-19 (COVID-19) pandemic is still devastating the world causing
significant social, economic, and political chaos. Corresponding to the absence of globally …

Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review

P Mikulska, M Malinowska, M Ignacyk, P Szustowski… - Pharmaceutics, 2023 - mdpi.com
In recent years, there has been a significant surge in reports on the health-promoting
benefits of winter cherry (Withania somnifera), also known as Ashwagandha. Its current …

Targeting COVID-19 (SARS-CoV-2) main protease through active phytocompounds of ayurvedic medicinal plants–Emblica officinalis (Amla), Phyllanthus niruri Linn …

S Murugesan, S Kottekad, I Crasta… - Computers in biology …, 2021 - Elsevier
Abstract Coronavirus Disease-2019 (COVID-19), a viral disease caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2) was declared a global pandemic by …

Spices and herbs: potential antiviral preventives and immunity boosters during COVID‐19

NA Singh, P Kumar, Jyoti, N Kumar - Phytotherapy Research, 2021 - Wiley Online Library
A severe acute respiratory syndrome is an unusual type of contagious pneumonia that is
caused by SARS coronavirus. At present, the whole world is trying to combat this …

Antiviral activity of sulfated polysaccharides from marine algae and its application in combating COVID-19: Mini review

N Hans, A Malik, S Naik - Bioresource technology reports, 2021 - Elsevier
Marine-derived sulfated polysaccharides possess various antiviral activities against a broad
range of enveloped and non-enveloped viruses. It has become the potential source of …

Complementary and alternative medicines use in COVID-19: A global perspective on practice, policy and research

V Paudyal, S Sun, R Hussain, MH Abutaleb… - Research in Social and …, 2022 - Elsevier
The COVID-19 pandemic has met international health systems with a low level of
preparedness and emergency response. While the emergence of effective vaccines has …

Traditional herbal medicines, bioactive metabolites, and plant products against COVID-19: update on clinical trials and mechanism of actions

S Alam, MMR Sarker, S Afrin, FT Richi… - Frontiers in …, 2021 - frontiersin.org
SARS-CoV-2 is the latest worldwide pandemic declared by the World Health Organization
and there is no established anti-COVID-19 drug to combat this notorious situation except …

[HTML][HTML] Applications of molecular docking in natural products-based drug discovery

I Asiamah, SA Obiri, W Tamekloe, FA Armah… - Scientific African, 2023 - Elsevier
Natural products have a long history of use in the treatment of various diseases particularly
in developing countries. The use of compounds of natural origin as lead compounds for the …

Biodiversity, Biochemical Profiling, and Pharmaco-Commercial Applications of Withania somnifera: A Review

H Gaurav, D Yadav, A Maurya, H Yadav, R Yadav… - Molecules, 2023 - mdpi.com
Withania somnifera L. Dunal (Ashwagandha), a key medicinal plant native to India, is used
globally to manage various ailments. This review focuses on the traditional uses, botany …