Stroke continues to be a significant cause of death and disability worldwide. Although major
advances have been made in the past decades in prevention, treatment, and rehabilitation …

Rodent animal models of stroke are widely used with brain ischemia inducible by various
occlusion methods. Permanent or transient occlusion of the distal portion of the middle …

There is increasing recognition that traumatic brain injury (TBI) may initiate long-term
neurodegenerative processes, particularly chronic traumatic encephalopathy. However …

There is insufficient evidence on the effect of nanoparticles, particularly liposomes loaded
with a statin, on acute ischemic stroke. We investigated the impact of atorvastatin-loaded …

Ceruloplasmin (Cp) is a ferroxidase that also plays a role in iron efflux from cells. It can thus
help to regulate cellular iron homeostasis. In the CNS, Cp is expressed as a membrane …

Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine with neuroprotective properties. Still, the
therapeutic potential of IL-6 after experimental stroke has not yet been investigated in a …

High levels of iron, measured as serum ferritin, are associated to a worse outcome after
stroke. However, it is not known whether ischemic damage might increase ferritin levels as …

Circulating extracellular vesicles (EVs) are proposed to participate in enhancing pathways of
recovery after stroke through paracrine signaling. To verify this hypothesis in a proof-of …

Background Vacuolar sorting protein 35 (VPS35), a critical component of retromer, is
essential for selective endosome-to-Golgi retrieval of membrane proteins. It is highly …

Recently, we have shown the differences in the early response of corticosterone and
inflammatory cytokines in the hippocampus and frontal cortex (FC) of rats with middle …