Alzheimer's disease (AD) is the most common neurodegenerative disease, which severely
threatens the health of the elderly and causes significant economic and social burdens. The …

The female mammalian brain exhibits sex hormone-driven plasticity during the reproductive
period. Recent evidence implicates chromatin dynamics in gene regulation underlying this …

Multivalent binding of CTCF to variable DNA sequences is thought to underlie its ability to
mediate diverse cellular functions. CTCF typically binds a 20 base-pair consensus DNA …

Numerous epidemiological studies have shown that PM 2.5 exposure in early life can
influence brain development and increase the risk of neurodevelopmental disorders in boys …

Open access to rodent cognitive data has lagged behind the rapid generation of large open-
access datasets in other areas of neuroscience, such as neuroimaging and genomics. One …

Cognitive aging is one of the major problems worldwide, especially as people get older. This
study aimed to perform global gene expression profiling of cognitive function to identify …

Abstract Synaptotagmin-7 (SYT7) has been proposed as an innovative therapeutic strategy
for treating cognitive impairment, while its contribution to Alzheimer's disease (AD) …

CCCTC-binding factor (CTCF) is a chromatin binding factor that binds to DNA sequence
specific sites and, together with cohesin complex, establishes chromatin loops and regulates …

Oligodendrocytes (OLs) are the myelinating glia of the CNS and are capable of
metabolically supporting long axonal projections by providing local fuel production. OL and …

As the proportions of the elderly are going up rapidly, the need to investigate factors that
impact the cognitive impairment process is of particular importance. With recent …