The transition from pregnancy to lactation (ie the transition period) is a time of significant
metabolic challenge, with a several-fold increase in a cow's requirement for energy, protein …

Simple Summary Cow–calf production is the foundation of the US beef industry. However,
infertility and sub-fertility limit its sustainability. In this review, we discuss the progress made …

Aberrant inflammation in the endometrium impairs reproduction and leads to poor fertility.
Small extracellular vesicles (sEV) are nanoparticles 30–200 nm in-size and contain …

Exosomes are a specific subpopulation of extracellular vesicles that are widely released by
cells of different origins with divergent functions that make their way into body fluids that can …

The current study evaluated exosomes isolated from plasma of heifers bred to have high or
low fertility through developing extreme diversity in fertility breeding values, however, key …

Cumulus cell expansion is required for the ovulation of a fertilizable oocyte. Extracellular
vesicles (EVs) are bilayer-lipid membrane vesicles that may be found in a variety of bodily …

Abnormal uterine function affects conception rate and embryo development, thereby leading
to poor fertility and reproduction failure. Exosomes are a nanosized subclass of extracellular …

In the past few decades, there has been a global decrease in dairy cow reproductive
performance. An activated inflammatory system, due to uterine infection, has been …

Disease susceptibility of dairy cows is greatest during the transition from pregnancy to
lactation. Circulating exosomes may provide biomarkers to detect at-risk cows to enhance …

The bovine immune system is known for its unusual traits relating to immunoglobulin and
antiviral responses. Peptidylarginine deiminases (PADs) are phylogenetically conserved …